Evidence map›Paper›PMID 38639354›Full record

ReviewJournal of the American Heart Association2024

Atrial Fibrillation After Patent Foramen Ovale Closure: Incidence, Pathophysiology, and Management.

Anastasios Apostolos, Dimitrios Tsiachris, Maria Drakopoulou, Georgios Trantalis, Georgios Oikonomou, Nikolaos Ktenopoulos, Chrysavgi Simopoulou, Odysseas Katsaros, Sotirios Tsalamandris, Constantina Aggeli and 3 more

Abstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anastasios ApostolosFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.ORCID 0000-0003-2616-7952
Dimitrios TsiachrisFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.ORCID 0000-0003-4531-9712
Maria DrakopoulouFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.ORCID 0000-0002-0022-0332
Georgios TrantalisFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.ORCID 0000-0001-6193-6329
Georgios OikonomouFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.ORCID 0000-0003-0144-0174
Nikolaos KtenopoulosFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.ORCID 0000-0002-0995-7015
Chrysavgi SimopoulouFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.ORCID 0000-0003-4223-3358
Odysseas KatsarosFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.ORCID 0000-0002-7684-3245
Sotirios TsalamandrisFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.ORCID 0000-0002-9945-930X
Constantina AggeliFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.
Georgios TsivgoulisSecond Department of Neurology, Medical School National and Kapodistrian University of Athens, Attikon University Hospital of Athens Athens Greece.ORCID 0000-0002-0640-3797
Costas TsioufisFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.
Konstantinos ToutouzasFirst Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippokration General Hospital Athens Greece.ORCID 0000-0002-7636-6725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This comprehensive review explores the incidence, pathophysiology, and management of atrial fibrillation (AF) following percutaneous closure of patent foramen ovale (PFO). Although AF is considered a common adverse event post PFO closure, its incidence, estimated at <5%, varies based on monitoring methods. The review delves into the challenging task of precisely estimating AF incidence, given subclinical AF and diverse diagnostic approaches. Notably, a temporal pattern emerges, with peak incidence around the 14th day after closure and a subsequent decline after the 45th day, mimicking general population AF trends. The pathophysiological mechanisms behind post PFO closure AF remain elusive, with proposed factors including local irritation, device-related interference, tissue stretch, and nickel hypersensitivity. Management considerations encompass rhythm control, with flecainide showing promise, and anticoagulation tailored to individual risk profiles. The authors advocate for a personalized approach, weighing factors like age, comorbidities, and device characteristics. Notably, postclosure AF is generally considered benign, often resolving spontaneously within 45 days, minimizing thromboembolic risks. Further studies are required to refine understanding and provide evidence-based guidelines.

Indexed as

Atrial FibrillationForamen Ovale, PatentCardiac CatheterizationHumansIncidencePostoperative ComplicationsRisk FactorsSeptal Occluder Devicearrhythmiasocclusionpatent foramen ovalereview

Identifiers

PMID38639354
PMCPMC11179870

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.