Evidence map›Paper›PMID 38639270›Full record

ReviewInfectious disorders drug targets2025

Recombinant ACE2 - Opportunities and Challenges in COVID-19 Treatment.

Mandeep Kaur, Rahul Sandhu, Akriti Aggarwal

Abstract readReview
PubMed Publisher
In one paragraph

Review in Infectious disorders drug targets, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Mandeep KaurGovernment Medical College, Patiala, Punjab, India.
Rahul SandhuDepartment of General Surgery, Armed Forces Medical College, Pune, Maharashtra, 411040, India.
Akriti AggarwalDepartment of Microbiology, Senior Resident, AIIMS Bathinda, Bathinda, India.
Armed Forces Medical College · INCentral University of Punjab · INGovernment Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It was in 2019 that the world experienced the devastation caused by SARS-CoV-2, contributing to a large number of deaths. This contagious virus not only challenged the health care system but has also hit the economy very badly. There has been a lot of research on effective vaccine development, and there has been some success in the same, but no effective antiviral drugs are available in the market. No doubt vaccination can prevent the disease, but it doesn't have the potential to cure an infected person, for which there is a dire need to develop some effective drug. Angiotensin convertase enzyme 2 (ACE2) played a substantial role in SARS-CoV-2 pathogenesis and thus has gained much attention during the pandemic. Moreover, it has opened up new avenues for the cure of COVID-19.

Indexed as

Angiotensin-Converting Enzyme 2Antiviral AgentsCOVID-19COVID-19 Drug TreatmentSARS-CoV-2HumansRecombinant ProteinsACE2 protein, humanAngiotensin-Converting Enzyme 2Antiviral AgentsRecombinant ProteinsACE2 downregulationCOVID-19COVID-19 treatment.hepatocytesKupffer cellsSARS-CoV-2

Identifiers

PMID38639270
OpenAlexW4394955109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.