Evidence map›Paper›PMID 38639197›Full record

ArticleOrganic & biomolecular chemistry2024

Discovery of selective monosaccharide receptors

Miguel Alena-Rodriguez, Marcos Fernandez-Villamarin, Ignacio Alfonso, Paula M Mendes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic & biomolecular chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miguel Alena-RodriguezSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, West Midlands, B15 2TT, UK. p.m.mendes@bham.ac.uk.
Marcos Fernandez-VillamarinSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, West Midlands, B15 2TT, UK. p.m.mendes@bham.ac.uk.
Ignacio AlfonsoDepartment of Biological Chemistry, Institute for Advanced Chemistry of Catalonia, IQAC-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.ORCID 0000-0003-0678-0362
Paula M MendesSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, West Midlands, B15 2TT, UK. p.m.mendes@bham.ac.uk.ORCID 0000-0001-6937-7293

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular recognition of saccharides by synthetic hosts has become an appealing but elusive task in the last decades. Herein, we combine Dynamic Combinatorial Chemistry (DCC) for the rapid self-assembly and screening of virtual libraries of receptors, with the use of ITC and NMR to validate the hits and molecular modelling to understand the binding mechanisms. We discovered a minimalistic receptor, 1F (

Indexed as

Combinatorial Chemistry TechniquesMonosaccharidesModels, MolecularPhenylalanineMonosaccharidesPhenylalanine

Identifiers

PMID38639197
PMCPMC11095087

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.