Evidence map›Paper›PMID 38638878›Full record

ArticleFrontiers in chemistry2024

Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV.

Kinga Pokrywka, Marta Grzechowiak, Joanna Sliwiak, Paulina Worsztynowicz, Joanna I Loch, Milosz Ruszkowski, Miroslaw Gilski, Mariusz Jaskolski

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kinga PokrywkaInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Marta GrzechowiakInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Joanna SliwiakInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Paulina WorsztynowiczInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Joanna I LochDepartment of Crystal Chemistry and Crystal Physics, Faculty of Chemistry, Jagiellonian University, Cracow, Poland.
Milosz RuszkowskiInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Miroslaw GilskiInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Mariusz JaskolskiInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
Institute of Bioorganic Chemistry, Polish Academy of Sciences · PLAdam Mickiewicz University in Poznań · PLJagiellonian University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ReAV, the inducible Class-3 L-asparaginase from the nitrogen-fixing symbiotic bacterium

Indexed as

amidohydrolasehydrolaseITCL-asparaginaseleukemiametalloproteinsite-directed mutagenesisX-ray crystallography

Identifiers

PMID38638878
PMCPMC11024299
OpenAlexW4393944737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.