Evidence map›Paper›PMID 38638877›Full record

ArticleFrontiers in chemistry2024

Integration of Wnt-inhibitory activity and structural novelty scoring results to uncover novel bioactive natural products: new Bicyclo[3.3.1]non-3-ene-2,9-diones from the leaves of

Luis-Manuel Quiros-Guerrero, Laurence Marcourt, Nathareen Chaiwangrach, Alexey Koval, Emerson Ferreira Queiroz, Bruno David, Antonio Grondin, Vladimir L Katanaev, Jean-Luc Wolfender

Abstract read
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In one paragraph

Article in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luis-Manuel Quiros-GuerreroInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Centre Médical Universitaire, Geneva, Switzerland.
Laurence MarcourtInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Centre Médical Universitaire, Geneva, Switzerland.
Nathareen ChaiwangrachCentre of Excellence in Cannabis Research, Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand.
Alexey KovalDepartment of Cell Physiology and Metabolism, Translational Research Centre in Oncohaematology, Faculty of Medicine, Geneva, Switzerland.
Emerson Ferreira QueirozInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Centre Médical Universitaire, Geneva, Switzerland.
Bruno DavidGreen Mission Department, Herbal Products Laboratory, Pierre Fabre Research Institute, Toulouse, France.
Antonio GrondinGreen Mission Department, Herbal Products Laboratory, Pierre Fabre Research Institute, Toulouse, France.
Vladimir L KatanaevDepartment of Cell Physiology and Metabolism, Translational Research Centre in Oncohaematology, Faculty of Medicine, Geneva, Switzerland.
Jean-Luc WolfenderInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Centre Médical Universitaire, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In natural products (NPs) research, methods for the efficient prioritization of natural extracts (NEs) are key for discovering novel bioactive NPs. In this study a biodiverse collection of 1,600 NEs, previously analyzed by UHPLC-HRMS

Indexed as

Hymenocardia punctata‘Inventa’ scoringmetabolomics (LC-MS)natural productsstructural elucidationstructural novelty discoveryWnt-pathwayWnt-pathway modulators

Identifiers

PMID38638877
PMCPMC11024435

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.