Evidence map›Paper›PMID 38638792›Full record

ArticleCureus2024

Cardiovascular Autonomic Nervous System in a Patient With Hereditary Angioedema Affected by COVID-19.

Beatrice De Maria, Monica Parati, Yagis Bey, Laura Adelaide Dalla Vecchia, Francesca Perego

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Beatrice De MariaDepartment of Internal Medicine, Istituti Clinici Scientifici Maugeri IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Milan, ITA.
Monica ParatiDepartment of Internal Medicine, Istituti Clinici Scientifici Maugeri IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Milan, ITA.
Yagis BeyDepartment of Internal Medicine, Istituti Clinici Scientifici Maugeri IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Milan, ITA.
Laura Adelaide Dalla VecchiaDepartment of Internal Medicine, Istituti Clinici Scientifici Maugeri IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Milan, ITA.
Francesca PeregoDepartment of Internal Medicine, Istituti Clinici Scientifici Maugeri IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), Milan, ITA.
Istituti Clinici Scientifici Maugeri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autonomic nervous system (ANS) regulation in hereditary angioedema (HAE) and coronavirus disease 2019 (COVID-19) is unknown. ANS alterations could be manifested during both the acute and post-acute phases of COVID-19. Implications of acute and chronic inflammation on ANS in HAE need to be addressed. In this case report, we monitored the systolic arterial blood pressure variability and baroreflex sensitivity in a female HAE patient both before experiencing COVID-19 symptoms and one month afterward. We also tracked the heart rate variability on the day preceding symptom onset, the day of symptom onset (SYM), the day following SYM, five days after SYM, the day of the first negative nasopharyngeal swab (i.e., 12 days after SYM), and one month after symptom onset. The results of this case report provide the characterization of vascular and cardiac autonomic profiles in an HAE patient until the resolution of an acute infection, a potential trigger for the acute HAE attack.

Indexed as

baroreflex sensitivityblood pressure variabilitycovid-19heart rate variability analysishereditary angioedema without normal c1 inhibitor

Identifiers

PMID38638792
PMCPMC11025019
OpenAlexW4392957443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.