Evidence map›Paper›PMID 38638376›Full record

ReviewJournal of clinical and translational hepatology2024

Effects of the Pituitary-targeted Gland Axes on Hepatic Lipid Homeostasis in Endocrine-associated Fatty Liver Disease-A Concept Worth Revisiting.

Yifang Li, Meina Zheng, Steven Limbara, Shanshan Zhang, Yutao Yu, Le Yu, Jian Jiao

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of clinical and translational hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yifang LiDepartment of Gastroenterology & Hepatology, China-Japan Union Hospital, Jilin University, Changchun, Jilin, China.
Meina ZhengDepartment of Gastroenterology & Hepatology, China-Japan Union Hospital, Jilin University, Changchun, Jilin, China.
Steven LimbaraDepartment of Gastroenterology & Hepatology, China-Japan Union Hospital, Jilin University, Changchun, Jilin, China.
Shanshan ZhangDepartment of Gastroenterology & Hepatology, China-Japan Union Hospital, Jilin University, Changchun, Jilin, China.
Yutao YuDepartment of Gastroenterology & Hepatology, China-Japan Union Hospital, Jilin University, Changchun, Jilin, China.
Le YuDepartment of Gastroenterology & Hepatology, China-Japan Union Hospital, Jilin University, Changchun, Jilin, China.
Jian JiaoDepartment of Gastroenterology & Hepatology, China-Japan Union Hospital, Jilin University, Changchun, Jilin, China.ORCID https://orcid.org/0000-0003-3751-2870
Union Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic lipid homeostasis is not only essential for maintaining normal cellular and systemic metabolic function but is also closely related to the steatosis of the liver. The controversy over the nomenclature of non-alcoholic fatty liver disease (NAFLD) in the past three years has once again sparked in-depth discussions on the pathogenesis of this disease and its impact on systemic metabolism. Pituitary-targeted gland axes (PTGA), an important hormone-regulating system, are indispensable in lipid homeostasis. This review focuses on the roles of thyroid hormones, adrenal hormones, sex hormones, and their receptors in hepatic lipid homeostasis, and summarizes recent research on pituitary target gland axes-related drugs regulating hepatic lipid metabolism. It also calls on researchers and clinicians to recognize the concept of endocrine-associated fatty liver disease (EAFLD) and to re-examine human lipid metabolism from the macroscopic perspective of homeostatic balance.

Indexed as

Endocrine-associated fatty liver disease (EAFLD)Lipid homeostasisMetabolismPituitary-target gland axes (PTGA)

Identifiers

PMID38638376
PMCPMC11022059
OpenAlexW4391116775

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.