Evidence map›Paper›PMID 38638226›Full record

ArticleChemical science2024

Aza-Achmatowicz rearrangement coupled with intermolecular aza-Friedel-Crafts enables total syntheses of uleine and aspidosperma alkaloids.

Foqing Ma, Yunlong Li, Kornkamon Akkarasereenon, Huiying Qiu, Yuen Tsz Cheung, Zhihong Guo, Rongbiao Tong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Foqing MaDepartment of Chemistry, The Hong Kong University of Science and Technology, Clearwater Bay Kowloon Hong Kong China rtong@ust.hk +86 23581594 +86 23587357.ORCID https://orcid.org/0000-0001-7449-0143
Yunlong LiDepartment of Chemistry, The Hong Kong University of Science and Technology, Clearwater Bay Kowloon Hong Kong China rtong@ust.hk +86 23581594 +86 23587357.
Kornkamon AkkarasereenonDepartment of Chemistry, The Hong Kong University of Science and Technology, Clearwater Bay Kowloon Hong Kong China rtong@ust.hk +86 23581594 +86 23587357.
Huiying QiuDepartment of Chemistry, The Hong Kong University of Science and Technology, Clearwater Bay Kowloon Hong Kong China rtong@ust.hk +86 23581594 +86 23587357.
Yuen Tsz CheungDepartment of Chemistry, The Hong Kong University of Science and Technology, Clearwater Bay Kowloon Hong Kong China rtong@ust.hk +86 23581594 +86 23587357.
Zhihong GuoDepartment of Chemistry, The Hong Kong University of Science and Technology, Clearwater Bay Kowloon Hong Kong China rtong@ust.hk +86 23581594 +86 23587357.ORCID https://orcid.org/0000-0003-0374-8412
Rongbiao TongDepartment of Chemistry, The Hong Kong University of Science and Technology, Clearwater Bay Kowloon Hong Kong China rtong@ust.hk +86 23581594 +86 23587357.ORCID https://orcid.org/0000-0002-2740-5222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspidosperma and uleine alkaloids belong to the large family of monoterpene indole alkaloids with diverse biological activities and thus have attracted extensive synthetic interest. Reported is the development of a new synthetic strategy that allows direct C3-C2' linkage of indoles with functionalized 2-hydroxypiperidines to construct the core common to all aspidoserma and uleine alkaloids. Such indole-piperidine linkage is enabled by coupling aza-Achmatowicz rearrangement (AAR) with indoles

Identifiers

PMID38638226
PMCPMC11023026

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.