Evidence map›Paper›PMID 38637940›Full record

ArticleEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2024

Risk factors influencing postoperative pleural empyema in patients with pleural mesothelioma: a retrospective single-centre analysis.

Peter Henschke, Laura Chiara Guglielmetti, Sven Hillinger, Gian-Marco Monsch, Didier Schneiter, Isabelle Opitz, Olivia Lauk

Open access · hybridAbstract read
In one paragraph

Article in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Empyema Caused byInfection and drug resistance · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Peter HenschkeDepartment of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.
Laura Chiara GuglielmettiDepartment of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.
Sven HillingerDepartment of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.
Gian-Marco MonschDepartment of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.
Didier SchneiterDepartment of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.
Isabelle OpitzDepartment of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0001-5900-9040
Olivia LaukDepartment of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland.
University Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPostoperative empyema is a severe, potentially lethal complication also present, but poorly studied in patients undergoing surgery for pleural mesothelioma. We aimed to analyse which perioperative characteristics might be associated with an increased risk for postoperative empyema.

methodsFrom September 1999 to February 2023 a retrospective analysis of consecutive patients undergoing surgery for pleural mesothelioma at the University Hospital of Zurich was performed. Uni- and multivariable logistic regression was used to identify associated risk factors of postoperative empyema after surgery.

resultsA total of 400 PM patients were included in the analysis, of which n = 50 patients developed empyema after surgery (12.5%). Baseline demographics were comparable between patients with (Eyes) and without empyema (Eno). 39% (n = 156) patients underwent extrapleural pneumonectomy (EPP), of whom 22% (n = 35) developed postoperative pleural empyema; 6% (n = 15) of the remaining 244 patients undergoing pleurectomy and decortication (n = 46), extended pleurectomy and decortication (n = 114), partial pleurectomy (n = 54) or explorative thoracotomy (n = 30) resulted in postoperative empyema. In multivariable logistic regression analysis, EPP (odds ratio 2.8, 95% confidence interval 1.5-5.4, P = 0.002) emerged as the only risk factor associated with postoperative empyema when controlled for smoking status. Median overall survival was significantly worse for Eyes (16 months, interquartile range 5-27 months) than for Eno (18 months, interquartile range 8-35 months).

conclusionsPatients undergoing EPP had a significantly higher risk of developing postoperative pleural empyema compared to patients undergoing other surgery types. Survival of patients with empyema was significantly shorter.

Indexed as

Empyema, PleuralPleural NeoplasmsPostoperative ComplicationsAgedFemaleHumansLung NeoplasmsMaleMesotheliomaMesothelioma, MalignantMiddle AgedPneumonectomyRetrospective StudiesRisk FactorsExtrapleural pleuropneumonectomyMacroscopic complete resectionMultimodal therapyPleural mesotheliomaPostoperative pleural empyema

Identifiers

PMID38637940
PMCPMC11055398
OpenAlexW4394934214

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.