Evidence map›Paper›PMID 38637726›Full record

SynthesisBMC cancer2024

Pretreatment quality of life and survival in patients with lung cancer: a systematic review and meta-analysis.

Taro Okayama, Katsuyoshi Suzuki, Shinichiro Morishita, Junichiro Inoue, Takashi Tanaka, Jiro Nakano, Takuya Fukushima

Erratum issuedAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pre-treatment quality of life and survival outcomes in lung cancer patients: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Feasibility and acceptability of ExerciseGuideUK for those living with and beyond lung cancer: a mixed methods study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Bibliometric and visual analysis of cancer-related insomnia research from 2015 to 2025.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Taro OkayamaDivision of Rehabilitation Medicine, Shizuoka Cancer Center, Shizuoka, Japan.
Katsuyoshi SuzukiDivision of Rehabilitation Medicine, Shizuoka Cancer Center, Shizuoka, Japan.
Shinichiro MorishitaDepartment of Physical Therapy, School of Health Science, Fukushima Medical University, Fukushima, Japan.
Junichiro InoueDivision of Rehabilitation Medicine, Kobe University Hospital International Clinical Cancer Research Center, Kobe, Japan.
Takashi TanakaDepartment of Rehabilitation, Hyogo Medical University Hospital, Nishinomiya, Japan.
Jiro NakanoFaculty of Rehabilitation, Kansai Medical University, Osaka, Japan.
Takuya FukushimaFaculty of Rehabilitation, Kansai Medical University, Osaka, Japan. fukustak@makino.kmu.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough many studies have explored the correlation between quality of life and survival, none have reported this relationship for specific cancers assessed at distinct time points. This meta-analysis aimed to investigate the impact of pretreatment Global Quality of Life (QOL) and functioning QOL, including physical, social, role, emotional, and cognitive QOLs, on mortality risk in patients with lung cancer.

methodsA literature search was conducted across the Cumulative Index to Nursing and Allied Health Literature (CINAHL), Scopus, and PubMed databases for articles published between their inception and December 2022. Subsequently, 11 studies were selected based on predefined eligibility criteria to investigate the relationship between pretreatment QOLs and mortality risk in patients with lung cancer.

resultsPretreatment global, physical, social, role, and emotional QOLs were significantly associated with mortality risk as follows: Global QOL (hazard ratio [HR] = 1.08 95% confidence interval [CI] = 1.03-1.13); Physical QOL (HR = 1.04 95% CI = 1.02-1.05); Social QOL (HR = 1.02 95% CI = 1.01-1.03; Role QOL (HR = 1.01 95% CI = 1.01-1.02); Emotional QOL (HR = 1.01 95% CI = 1.00-1.03).

conclusionsThese findings underscore the importance of early QOL assessment after diagnosis as well as early provision of physical, social, and psychological support accommodating each patient's demands.

trial registrationThe International Prospective Register of Systematic Reviews registration number CRD42023398206, Registered on February 20, 2023.

Indexed as

Lung NeoplasmsAnxietyDepressionEmotionsHumansQuality of LifeLung cancerMeta-analysisMortality riskQuality of lifeSystematic review

Identifiers

PMID38637726
PMCPMC11027547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.