Evidence map›Paper›PMID 38637718›Full record

ArticleInternational journal of obesity (2005)2024

Association between BMI-based metabolic phenotypes and prevalence of intracranial atherosclerotic stenosis: a cross-sectional study.

Xue Xia, Xinsheng Han, Guangxin Xia, Xingquan Zhao, Anxin Wang

Abstract read
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In one paragraph

Article in International journal of obesity (2005), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Current perspectives on the pathogenesis of cerebral atherosclerosis.Journal of inflammation (London, England) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xue Xia *Department of Epidemiology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, 100070, Beijing, China.ORCID 0000-0002-1719-0598
Xinsheng Han *Department of Neurology, Kaifeng Central Hospital, Xinxiang Medical University, Kaifeng, 475000, China.
Guangxin Xia *Department of Neurology, Kaifeng Central Hospital, Xinxiang Medical University, Kaifeng, 475000, China.ORCID 0000-0003-1926-1449
Xingquan ZhaoDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, 100070, Beijing, China. zxq@vip.163.com.ORCID 0000-0001-8345-5147
Anxin WangDepartment of Epidemiology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, 100070, Beijing, China. wanganxin@bjtth.org.ORCID 0000-0003-4351-2877
Capital Medical University · CNKaifeng University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity and metabolic syndrome (MetS) have been acknowledged to commonly co-exist and lead to increased risks of stroke, whereas the association between various BMI-based metabolic phenotypes and development of intracranial atherosclerotic stenosis (ICAS) remained controversial.

methodsA total of 5355 participants were included from the Asymptomatic Polyvascular Abnormalities Community (APAC) study. Participants were categorized into six groups according to their body mass index (BMI) and MetS status. ICAS was assessed using transcranial Doppler (TCD) Ultrasonography. Logistic regression was employed to evaluate the association between BMI-based metabolic phenotypes and ICAS.

results704 participants were diagnosed with ICAS. Compared to the metabolic healthy normal weight (MH-NW) group, the metabolic unhealthy normal weight (MUH-NW) group demonstrated a higher risk of ICAS (full-adjusted odds ratio [OR], 1.91; 95% confidence interval [CI], 1.42-2.57), while no significant association was observed in the metabolic unhealthy obesity (MUO) group (full-adjusted OR, 1.07; 95% CI, 0.70-1.65) and other metabolic healthy groups regardless of BMI. The results were consistent across gender, age, smoking, alcohol intake, and physical activity subgroups.

conclusionThe present study suggested that MUH-NW individuals had a significant association with increased risk of ICAS compared with MH-NW individuals.

Indexed as

Body Mass IndexIntracranial ArteriosclerosisMetabolic SyndromePhenotypeAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedObesityPrevalenceRisk FactorsUltrasonography, Doppler, TranscranialBody mass indexIntracranial atherosclerotic stenosisLipoproteinMetabolic syndrome

Identifiers

PMID38637718
OpenAlexW4394913855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.