SynthesisScientific reports2024
Effects of human milk odor stimulation on feeding in premature infants: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Impact of breast milk odor exposure on first oral feeding performance in preterm infants following non-nutritive sucking.Journal of perinatology : official journal of the California Perinatal Association · 2026Trial
- The effect of breast milk and vanilla odor on duration of transition from gavage to oral feeding in premature infants.Scientific reports · 2026Trial
- Pacifier use in preterm infants during orogastric tube feeding: a randomized trial.Revista da Associacao Medica Brasileira (1992) · 2026Trial
- Effectiveness of Breast Milk Odor on Preterm Infant Feeding Cues: Protocol for a Randomized Clinical Trial.JMIR research protocols · 2026Article
- Breastfeeding, bonding, and olfaction: unlocking the potential of mother-infant odour exchange.EBioMedicine · 2026Review
- The influence of family care guidance for premature infants based on a telemedicine model on their neurodevelopmental assessment indicators.Frontiers in pediatrics · 2026Article
- Recent Advancements and Best Practices in Supporting Newborn Feeding: A Narrative Review.Pediatric clinics of North America · 2025Review
- Effect of Smell and Taste of Milk on Feeding Parameters in Preterm Neonates: An Updated Meta-Analysis.Cureus · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies suggested odor stimulation may influence feeding of premature neonates. Therefore, this systematic review and meta-analysis of randomized controlled trials was conducted to assess the effect of human milk odor stimulation on feeding of premature infants. All randomized controlled trials related to human milk odor stimulation on feeding in premature infants published in PubMed, Cochrane, Library, Medline, Embase, Web of science databases and Chinese biomedical literature databases, China National Knowledge Infrastructure, China Science and Technology Journal Database (VIP) and Wanfang Chinese databases were searched, and The Cochrane Handbook 5.1.0 was used to evaluate the quality and authenticity of the literature. Relevant information of the included studies was extracted and summarized, and the evaluation indexes were analyzed using ReviewManager5.3. The retrieval time was from the establishment of the database to July 28, 2022.12 articles were assessed for eligibility, and six randomized controlled studies were eventually included in the meta-analysis (PRISMA). A total of 6 randomized controlled studies with 763 patients were finally included in the study, and the quality evaluation of literatures were all grade B. Human milk odor stimulation reduced the transition time to oral feeding in premature infants [SMD = - 0.48, 95% CI (- 0.69, - 0.27), Z = 4.54, P < 0.00001] and shortened the duration of parenteral nutrition [MD = - 1.01, 95% CI (- 1.70, - 0.32), Z = 2.88, P = 0.004]. However, it did not change the length of hospitalization for premature infants [MD = - 0.03, 95% CI (- 0.41, 0.35), Z = 0.17, P = 0.86]. The implementation of human milk odor stimulation can reduce the transition time to oral feeding and the duration of parenteral nutrition in premature infants, but further studies are needed to determine whether it can reduce the length of hospital stay in premature infants. More high-quality, large-sample studies are needed to investigate the effect of human milk odor stimulation on the feeding process and other outcomes in premature infants.
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