ReviewAnnual review of vision science2024
Insights into Myopia from Mouse Models.
Review in Annual review of vision science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Model of naturally occurring refractive error (NORE) in mice.bioRxiv : the preprint server for biology · 2026Article
- Dual-Hit Myopia Mechanism Unveiled by Multi-Omics: Opn1mw Deficiency Primed the Retina for Exaggerated Response to Environmental Defocus.Investigative ophthalmology & visual science · 2026Article
- Examining murine eye length asymmetry with spectral domain optical coherence tomography.Experimental eye research · 2025Article
- Genetic influences on intergenerational refractive error shifts and extreme myopia.The British journal of ophthalmology · 2025Article
- Article
- Studies of All-trans Retinoic Acid Transport in the Eye.Investigative ophthalmology & visual science · 2025Article
- Nonlinear pathological trajectory of a high-myopia C57/BL6J mouse model induced by form deprivation.Frontiers in physiology · 2024Article
- Meta-analysis of retinal transcriptome profiling studies in animal models of myopia.Frontiers in medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Animal models are critical for understanding the initiation and progression of myopia, a refractive condition that causes blurred distance vision. The prevalence of myopia is rapidly increasing worldwide, and myopia increases the risk of developing potentially blinding diseases. Current pharmacological, optical, and environmental interventions attenuate myopia progression in children, but it is still unclear how this occurs or how these interventions can be improved to increase their protective effects. To optimize myopia interventions, directed mechanistic studies are needed. The mouse model is well-suited to these studies because of its well-characterized visual system and the genetic experimental tools available, which can be combined with pharmacological and environmental manipulations for powerful investigations of causation. This review describes aspects of the mouse visual system that support its use as a myopia model and presents genetic, pharmacological, and environmental studies that significantly contribute to our understanding of the mechanisms that underlie myopigenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.