Evidence map›Paper›PMID 38635868›Full record

ReviewAnnual review of neuroscience2024

Development of the Binocular Circuit.

Eloísa Herrera, Alain Chédotal, Carol Mason

Abstract readReview
In one paragraph

Review in Annual review of neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Binocular Circuitry as a Model for Understanding Experience-Dependent Circuit Development across the Mammalian Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Review
  2. A Critical Look at Critical Periods.Annual review of vision science · 2025
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eloísa HerreraInstituto de Neurociencias (CSIC-UMH), Consejo Superior de Investigaciones Científicas and Universidad Miguel Hernández, Alicante, Spain; email: e.herrera@umh.es.
Alain ChédotalUniversité Claude Bernard Lyon 1, MeLiS, CNRS UMR5284, INSERM U1314, Lyon, France.
Carol MasonDepartments of Pathology and Cell Biology, Neuroscience, and Ophthalmology, Zuckerman Institute, Columbia University, New York, NY, USA; email: cam4@columbia.edu.

Funding

The Role of Zic Genes in Patterning the Binocular ProjectionR01EY015290 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MASON, CAROL A. · 2004 to 2023
$7.6M
GROWTH AND GUIDANCE OF RETINAL AXONSR01EY012736 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MASON, CAROL A. · 1999 to 2017
$6.4M
RPE-Neural Retina Interactions in the Developing Albino EyeR21EY023714 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MASON, CAROL A. · 2014 to 2015
$436k
NEI NIH HHS R01 EY012736NEI NIH HHS R01 EY015290NEI NIH HHS R21 EY023714
6 · The paper itself

Abstract

Seeing in three dimensions is a major property of the visual system in mammals. The circuit underlying this property begins in the retina, from which retinal ganglion cells (RGCs) extend to the same or opposite side of the brain. RGC axons decussate to form the optic chiasm, then grow to targets in the thalamus and midbrain, where they synapse with neurons that project to the visual cortex. Here we review the cellular and molecular mechanisms of RGC axonal growth cone guidance across or away from the midline via receptors to cues in the midline environment. We present new views on the specification of ipsi- and contralateral RGC subpopulations and factors implementing their organization in the optic tract and termination in subregions of their targets. Lastly, we describe the functional and behavioral aspects of binocular vision, focusing on the mouse, and discuss recent discoveries in the evolution of the binocular circuit.

Indexed as

Retinal Ganglion CellsVision, BinocularVisual PathwaysAnimalsHumansRetinaVisual Cortexaxon targetingciliary marginevolutionoptic chiasmretinal ganglion celltranscriptomics

Identifiers

PMID38635868
PMCPMC12447952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.