Evidence map›Paper›PMID 38635764›Full record

ArticleBlood2024

Cost-effectiveness of prophylaxis with recombinant vs plasma-derived VWF in severe von Willebrand disease in the United States.

Christina Waldron, Satoko Ito, Daniel Wang, Cecily Allen, Giri Viswanathan, Robert D Bona, Adam Cuker, George Goshua

Open access · greenAbstract readComparative Study
In one paragraph

Article in Blood, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Christina WaldronYale School of Medicine, New Haven, CT.ORCID 0000-0003-0286-6599
Satoko ItoSection of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT.
Daniel WangYale School of Medicine, New Haven, CT.ORCID 0000-0002-9336-4123
Cecily AllenDivision of Hematology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD.ORCID 0000-0001-7972-7605
Giri ViswanathanYale College, New Haven, CT.
Robert D BonaSection of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT.
Adam CukerDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
George GoshuaSection of Hematology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT.ORCID 0000-0002-1624-4427
Yale University · USJohns Hopkins Hospital · USUniversity of Pennsylvania · USYale New Haven Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Short-Term Reserch Training: Students in Health SchoolsT35HL007649 · NHLBI · YALE UNIVERSITY · PI Sarwat I Chaudhry, Erica L Herzog · 1987 to 2026
$5.7M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS T35 HL007649
6 · The paper itself

Abstract

abstractWe evaluated the cost-effectiveness of prophylaxis with recombinant von Willebrand factor (rVWF) vs with plasma-derived von Willebrand factor (pdVWF) for patients with severe Von Willebrand disease. We found that rVWF is a cost-saving factor replacement compared with pdVWF across all willingness-to-pay thresholds in the United States.

Indexed as

Cost-Benefit AnalysisRecombinant Proteinsvon Willebrand Diseasesvon Willebrand FactorFemaleHumansMaleUnited StatesRecombinant Proteinsvon Willebrand Factor

Identifiers

PMID38635764
PMCPMC11862817
OpenAlexW4394909621

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.