ArticlePloS one2024
Sex as a risk factor regarding presbyopia in the rhesus monkey.
Mary Ann Croft, Jared P Mcdonald, Julie Kiland, Julie A Mattison, George S Roth, Don Ingram, Paul L Kaufman
Open access · goldAbstract read
In one paragraphArticle in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors at 5 institutions in 1 country.
Mary Ann CroftDepartment of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, United States of America.
Jared P McdonaldDepartment of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, United States of America.
Julie KilandDepartment of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, United States of America.
Julie A MattisonTranslational Gerontology Branch, National Institute on Aging, NIH, Dickerson, MD, United States of America.
George S RothGeroScience Inc. and Prolongevity Technologies LLC, Pylesville, MD, United States of America.
Don IngramPennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, United States of America.
Paul L KaufmanDepartment of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, United States of America.
University of Wisconsin–Madison · USLouisiana State University · USNational Institute on Aging · USSmith-Kettlewell Eye Research Institute · USVeroscience (United States) · US
Funding
WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7MZOLEDRONATE PREVENTS BONE LOSS IN OVARIECTOMIZED RHESUS MONKEYSP51RR000167 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI KAUFMAN, PAUL L · 1985 to 2011
$106.7MPrimate Aging StudiesZIAAG000371 · NIA · NATIONAL INSTITUTE ON AGING · PI MATTISON, JULIE · 2010 to 2025
$13.7MUW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI Donna M Peters · 2005 to 2026
$12.6MExtralenticular Aspects of Accommodation and PresbyopiaR01EY025359 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI KAUFMAN, PAUL L · 2016 to 2019
$2.5MCILIARY MUSCLE AGINGR01EY010213 · NEI · UNIVERSITY OF WISCONSIN MADISON · PI KAUFMAN, PAUL LEON · 1996 to 2004
$1.4MExtra-lenticular aspects of accommodation and presbyopiaR21EY018370 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI KAUFMAN, PAUL L · 2009 to 2010
$784kNCRR NIH HHS P51 RR000167NEI NIH HHS P30 EY016665NEI NIH HHS R01 EY010213NEI NIH HHS R01 EY025359NEI NIH HHS R21 EY018370NIH HHS P51 OD011106
6 · The paper itselfAbstract
purposeTo determine the effect of sex as a risk factor regarding presbyopia.
methodsMaximum accommodation was pharmacologically induced (40% cabachol corneal iontophoresis) in 97 rhesus monkeys (49 males and 48 females) ranging in age from 8 to 36 years old. Accommodation was measured by Hartinger coincidence refractometry.
resultsAccommodative amplitude measured refractometrically decreased with age, and the rate of change was not different between males and females (p = 0.827).
conclusionsPresbyopia is essentially sex neutral, and no one is spared. There may be modest variations between different populations for various reasons, but essentially it is monotonously predictable. At present there is no biological therapeutic.
Indexed as
Lens, CrystallinePresbyopiaAccommodation, OcularAgingAnimalsFemaleMacaca mulattaMale
Identifiers
PMID38635668
PMCPMC11025728
OpenAlexW4394910023
What OpenQuestion holds
Textmetadata
LicenceCC BY
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