ArticlePloS one2024
Incidence rates of the most common canine tumors based on data from the Swiss Canine Cancer Registry (2008 to 2020).
Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 39 citations in OpenAlex.
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- A review of spontaneous bone metastases in domestic and laboratory animals.Journal of bone oncology · 2026Review
- Epidemiology of Four Major Canine Tumours in the UK: Insights From a National Pathology Registry With Comparative Oncology Perspectives.Veterinary and comparative oncology · 2026Article
- Bacillus thuringiensis as a factory producing parasporin toxins with promising anticancer properties: a review.Microbial cell factories · 2026Review
- Pre-contrast computed tomography reveals distinct characteristics and anatomical distribution of presumably lymphomatous lymph nodes in canine multicentric lymphoma.Veterinary world · 2026Article
- Metabolomic profiling and anti-tumor function of canine NK cells in tumor interaction.BMC veterinary research · 2026Article
- Ultrasonographic and computed tomographic findings of an intra-abdominal lipoma in a dog.Veterinary research communications · 2026Article
- Factors influencing malignant tumor development in cats from a multicenter retrospective study.Scientific reports · 2026Article
- The epidemiological landscape of canine tumors in central Italy: animal cancer registry insights, distribution patterns, and incidence estimates.Frontiers in veterinary science · 2026Article
- Innovative Chorioallantoic Membrane Model as Valuable Tool in Diagnostics and Testing of Domestic Animal Cancers.Transboundary and emerging diseases · 2026Review
- Trimodal cytological integration of micronuclei assay, argyrophilic nucleolar organizer region staining, and cytomorphometry enhances diagnostic discrimination of canine gingival masses.Veterinary world · 2026Article
- Every Tumour Counts: A Comprehensive Overview of Canine Oncology in Portugal.Animals : an open access journal from MDPI · 2025Article
- Synchronous uterine leiomyosarcoma and pulmonary adenocarcinoma in a meerkat (Suricata suricatta): a case report.BMC veterinary research · 2025Article
- Multiplexed immunoassay for a serum autoantibody biomarker panel in diagnostic and prognostic prediction of canine mammary tumors.The veterinary quarterly · 2025Article
- Knowledge, Perceptions, Attitudes, and Practices of Dog and Cat Owners Regarding Skin Tumors: A Cross-Sectional Study.Veterinary sciences · 2025Article
- Large-scale epidemiological and diagnostic assessment of canine cytology in Portugal: insights from 12,671 retrospective cases.Veterinary world · 2025Article
- Comparative Genetics of Canine and Human Cancers.Veterinary sciences · 2025Review
- BRAF Mutation Analysis: A Retrospective Evaluation of 8365 Diagnostic Samples with a Special View on Canine Breeds (2018-2024).Veterinary sciences · 2025Article
- Risk Factors for the Occurrence of Cutaneous Neoplasms in Dogs: A Retrospective Study by Cytology Reports, 2019-2021.Animals : an open access journal from MDPI · 2025Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Monitoring neoplasms in standardized registries facilitates epidemiologic studies of risk factors for tumor development and predisposition. In an observational study, we determined incidence rates (IR) and malignant tumor incidence rate ratios (IRR) by age, sex, and breed in Swiss dogs using demographic data from the official Swiss dog registration database Amicus. The dataset analyzed included 54'986 tumors diagnosed by histology and cytology in four Swiss veterinary pathology laboratories between 2008 and 2020. Diagnoses were coded according to the Vet-ICD-O-canine-1 system. Most tumors occurred in the skin (n = 19'045; 34.64%), soft tissues (n = 11'092; 20.17%), and mammary glands (n = 7'974; 14.50%). The IRs for all and for malignant tumors were 775/100'000 dog-years at risk (95%CI 764-777) and 338/100'000 dog-years at risk (95%CI 333-342), respectively. Females (850; 95%CI 834-853) had a higher overall tumor IR than males (679; 95%CI 666-684). The highest tumor IR was found at 11 years of age (1'857; 95%CI 1'780-1'867). Potential novel breed-specific predispositions were uncovered, with high IRs for several benign and malignant tumors in Polski Owczarek Nizinnys (overall IR: 3'303; 95%CI 2'502-3'864) and high IRs for malignant tumors in Russian Black Terriers (melanomas: 345; 95%CI 138-708), Field Spaniels (adenocarcinomas: 376; CI95% 138-817), Dogo Argentinos (mast cell tumors: 844; CI95% 591-1'169), King Charles Spaniels and Manchester Terriers (lymphomas: 319; CI95% 137-627 and 302; CI95% 98-704, respectively), Landseers (osteosarcomas: 74; CI95% 15-216), Bouvier des Flandres (hemangiosarcomas: 127; CI95% 26-371), and Bearded Collies and Cane Corso Italianos (gliomas: 91; CI95% 45-162 and 34; CI95% 7-99, respectively). Nordic hunting dogs had the highest (8.08; CI95% 3.55-16.7) and Chihuahueno the lowest cancer IRRs (0.42; 95%CI 0.31-0.57) compared to mixed breeds. In conclusion, the calculated IRs and IRRs revealed previously unknown predisposing factors, including novel breed-specific susceptibilities. The results may have implications for cancer screening, diagnostic work-up, breeding management and oncologic and translational research.
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