Evidence map›Paper›PMID 38635024›Full record

ArticleJournal of assisted reproduction and genetics2024

Rescue intrauterine insemination in women failing to retrieve oocytes at ovum pick-up: report of a case series.

Ludovico Muzii, Giulia Galati, Ilenia La Barbiera, Antonella Linari, Oriana Capri, Daniela Pietrangeli, Edgardo Somigliana

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In one paragraph

Article in Journal of assisted reproduction and genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ludovico MuziiDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161, Rome, Italy.
Giulia GalatiDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161, Rome, Italy. giulia.galati@uniroma1.it.ORCID http://orcid.org/0000-0002-5289-4013
Ilenia La BarbieraDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161, Rome, Italy.
Antonella LinariDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161, Rome, Italy.
Oriana CapriDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161, Rome, Italy.
Daniela PietrangeliDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, 00161, Rome, Italy.
Edgardo SomiglianaDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFailure to collect oocytes at the time of oocyte pick-up is an unfavorable outcome of in vitro fertilization (IVF) cycles. In these cases, prompt intrauterine insemination (IUI) could be an option (rescue IUI), but this possibility has been poorly studied.

methodsRescue IUI is routinely offered in our unit in women failing to retrieve oocytes, provided that they have at least one patent tube, normal male semen analysis, and the total number of developed follicles is ≤ 3. We therefore reviewed all oocyte retrievals performed from 2006 to 2022 in our unit to identify these cases. As a comparator, we referred to preplanned IUI performed during the same study period. The 95% confidence interval (95% CI) of proportions was calculated using a binomial distribution model.

resultsRescue IUI was performed in 96 out of 3531 oocyte retrievals (2.7%; 95% CI 2.2-3.3%). Six live births were obtained, corresponding to 6.2% (95% CI 2.3-13.1). All pregnancies were singletons.

conclusionsRescue IUI in women failing to retrieve oocytes is a possible option that may be considered in selected cases. The efficacy is low, but the procedure is simple, and without significant risks. Generalizability to a conventional IVF protocol setting is however limited.

Indexed as

Fertilization in VitroOocyte RetrievalOocytesPregnancy RateAdultFemaleHumansInsemination, ArtificialLive BirthMaleOvulation InductionPregnancyIntrauterine inseminationIVFOocytePick-up

Identifiers

PMID38635024
PMCPMC11224174

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