Evidence map›Paper›PMID 38634877›Full record

ArticleEuropean radiology2024

Artificial intelligence for automated detection and measurements of carpal instability signs on conventional radiographs.

Nils Hendrix, Ward Hendrix, Bas Maresch, Job van Amersfoort, Tineke Oosterveld-Bonsma, Stephanie Kolderman, Myrthe Vestering, Stephanie Zielinski, Karlijn Rutten, Jan Dammeier and 3 more

Open access · hybridAbstract read
In one paragraph

Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Nils HendrixDepartment of Medical Imaging, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands. nils.hendrix@radboudumc.nl.ORCID http://orcid.org/0000-0003-3332-6245
Ward HendrixDepartment of Medical Imaging, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Bas MareschDepartment of Radiology, Ziekenhuis Gelderse Vallei, Willy Brandtlaan 10, 6717 RP, Ede, The Netherlands.
Job van AmersfoortDepartment of Surgery, Ziekenhuis Gelderse Vallei, Willy Brandtlaan 10, 6717 RP, Ede, The Netherlands.
Tineke Oosterveld-BonsmaDepartment of Radiology, Ziekenhuis Gelderse Vallei, Willy Brandtlaan 10, 6717 RP, Ede, The Netherlands.
Stephanie KoldermanDepartment of Radiology, Ziekenhuis Gelderse Vallei, Willy Brandtlaan 10, 6717 RP, Ede, The Netherlands.
Myrthe VesteringDepartment of Radiology, Ziekenhuis Gelderse Vallei, Willy Brandtlaan 10, 6717 RP, Ede, The Netherlands.
Stephanie ZielinskiDepartment of Surgery, Ziekenhuis Gelderse Vallei, Willy Brandtlaan 10, 6717 RP, Ede, The Netherlands.
Karlijn RuttenDepartment of Medical Imaging, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Jan DammeierDepartment of Medical Imaging, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Lee-Ling Sharon OngJheronimus Academy of Data Science, Sint Janssingel 92, 5211 DA, 's-Hertogenbosch, The Netherlands.
Bram van GinnekenDepartment of Medical Imaging, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Matthieu RuttenDepartment of Medical Imaging, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLZiekenhuis Gelderse Vallei · NLTilburg University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo develop and validate an artificial intelligence (AI) system for measuring and detecting signs of carpal instability on conventional radiographs. MATERIALS AND

methodsTwo case-control datasets of hand and wrist radiographs were retrospectively acquired at three hospitals (hospitals A, B, and C). Dataset 1 (2178 radiographs from 1993 patients, hospitals A and B, 2018-2019) was used for developing an AI system for measuring scapholunate (SL) joint distances, SL and capitolunate (CL) angles, and carpal arc interruptions. Dataset 2 (481 radiographs from 217 patients, hospital C, 2017-2021) was used for testing, and with a subsample (174 radiographs from 87 patients), an observer study was conducted to compare its performance to five clinicians. Evaluation metrics included mean absolute error (MAE), sensitivity, and specificity.

resultsDataset 2 included 258 SL distances, 189 SL angles, 191 CL angles, and 217 carpal arc labels obtained from 217 patients (mean age, 51 years ± 23 [standard deviation]; 133 women). The MAE in measuring SL distances, SL angles, and CL angles was respectively 0.65 mm (95%CI: 0.59, 0.72), 7.9 degrees (95%CI: 7.0, 8.9), and 5.9 degrees (95%CI: 5.2, 6.6). The sensitivity and specificity for detecting arc interruptions were 83% (95%CI: 74, 91) and 64% (95%CI: 56, 71). The measurements were largely comparable to those of the clinicians, while arc interruption detections were more accurate than those of most clinicians.

conclusionThis study demonstrates that a newly developed automated AI system accurately measures and detects signs of carpal instability on conventional radiographs. CLINICAL RELEVANCE STATEMENT: This system has the potential to improve detections of carpal arc interruptions and could be a promising tool for supporting clinicians in detecting carpal instability.

Indexed as

Artificial IntelligenceJoint InstabilityAdultAgedCarpal BonesCarpal JointsCase-Control StudiesFemaleHumansMaleMiddle AgedRadiographyRetrospective StudiesSensitivity and SpecificityWrist JointArtificial intelligenceRadiographyWrist

Identifiers

PMID38634877
PMCPMC11399222
OpenAlexW4394917945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.