Evidence map›Paper›PMID 38634849›Full record

ArticleUlusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES2024

The role of ischemia-modified albumin, presepsin, delta neutrophil index, and inflammatory markers in diagnosing acute cholecystitis.

Muhammed Semih Gedik, Ali Ihsan Kilci, Hakan Hakkoymaz, Muhammed Seyithanoğlu, Muhammed Alperen Orakçı, Nuri Mehmet Basan, Arif Aksu, Ömer Faruk Küçük

Open access · bronzeAbstract read
In one paragraph

Article in Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Muhammed Semih GedikDepartment of Emergency Medicine, Sütçü İmam University Faculty of Medicine, Kahramanmaraş-Türkiye.
Ali Ihsan KilciDepartment of Emergency Medicine, Sütçü İmam University Faculty of Medicine, Kahramanmaraş-Türkiye.
Hakan HakkoymazDepartment of Emergency Medicine, Sütçü İmam University Faculty of Medicine, Kahramanmaraş-Türkiye.
Muhammed SeyithanoğluDepartment of Medical Biochemistry, Sütçü İmam University Faculty of Medicine, Kahramanmaraş-Türkiye.
Muhammed Alperen OrakçıDepartment of General Surgery, Kayseri State Hospital, Kayseri-Türkiye.
Nuri Mehmet BasanDepartment of Neurology, Başakşehir Çam ve Sakura State Hospital, İstanbul-Türkiye.
Arif AksuDepartment of Emergency Medicine, Adana State Hospital, Adana-Türkiye.
Ömer Faruk KüçükDepartment of Emergency Medicine, Sütçü İmam University Faculty of Medicine, Kahramanmaraş-Türkiye.
Kahramanmaraş Sütçü İmam University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study is to determine the significance of markers such as C-reactive protein, procalcitonin, complete blood count parameters, delta neutrophil index, ischemia-modified albumin, presepsin, and oxidative stress indicators, which are associated with inflammation, oxidative stress, and ischemia in the pathology and diagnosis of acute cholecystitis in adults.

methodsPatients diagnosed with acute cholecystitis in the emergency department and healthy individuals in the control group were included in the study. Routine blood count and biochemistry analyses were performed on the participants. Blood serum was used to measure ischemia-modified albumin, presepsin, and oxidative stress indicators.

resultsWhite blood cell count, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, delta neutrophil index, C-reactive protein, procalcitonin, ischemia-modified albumin, ischemia-modified albumin to albumin ratio, presepsin, and oxidative stress indicators were significantly higher in patients with cholecystitis compared to the control group. Measurements of white blood cell count, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and delta neutrophil index can be included as part of the complete blood count. The complete blood count parameters are readily available and do not incur additional costs to the healthcare system.

conclusionThe authors believe that the neutrophil-to-lymphocyte ratio, delta neutrophil index, ischemia-modified albumin, ischemia-modified albumin to albumin ratio, and presepsin values can be used as new markers in the diagnosis of acute cholecystitis due to their high sensitivity, specificity, and low negative likelihood ratio.

Indexed as

Cholecystitis, AcuteNeutrophilsSerum Albumin, HumanAdultBiomarkersC-Reactive ProteinHumansIschemiaLipopolysaccharide ReceptorsPeptide FragmentsProcalcitoninSerum AlbuminBiomarkersC-Reactive Proteinischemia-modified albuminLipopolysaccharide ReceptorsPeptide Fragmentspresepsin protein, humanProcalcitoninSerum AlbuminSerum Albumin, Human

Identifiers

PMID38634849
PMCPMC11065968
OpenAlexW4394017149

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.