Evidence map›Paper›PMID 38634810›Full record

ArticleACS biomaterials science & engineering2024

Enhanced Vascular-like Network Formation of Encapsulated HUVECs and ADSCs Coculture in Growth Factors Conjugated GelMA Hydrogels.

Sasinan Bupphathong, Joshua Lim, Hsu-Wei Fang, Hsuan-Ya Tao, Chen-En Yeh, Tian-An Ku, Wei Huang, Ting-Yu Kuo, Chih-Hsin Lin

Open access · hybridAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Conjugation of Proangiogenic Peptide to Enhance a Soft Tissue Bioink.Journal of biomedical materials research. Part A · 2025
    Article
  7. Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sasinan BupphathongGraduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-1897-655X
Joshua LimGraduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.
Hsu-Wei FangHigh-Value Biomaterials Research and Commercialization Center, National Taipei University of Technology, Taipei 10608, Taiwan.
Hsuan-Ya TaoGraduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.
Chen-En YehSchool of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.
Tian-An KuSchool of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.
Wei HuangDepartment of Orthodontics, Rutgers School of Dental Medicine, Newark, New Jersey 07103, United States.
Ting-Yu KuoSchool of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.
Chih-Hsin LinGraduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-7381-5938
Taipei Medical University · TWNational Taipei University of Technology · TWRutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering primarily aimed to alleviate the insufficiency of organ donations worldwide. Nonetheless, the survival of the engineered tissue is often compromised due to the complexity of the natural organ architectures, especially the vascular system inside the organ, which allows food-waste transfer. Thus, vascularization within the engineered tissue is of paramount importance. A critical aspect of this endeavor is the ability to replicate the intricacies of the extracellular matrix and promote the formation of functional vascular networks within engineered constructs. In this study, human adipose-derived stem cells (hADSCs) and human umbilical vein endothelial cells (HUVECs) were cocultured in different types of gelatin methacrylate (GelMA). In brief, pro-angiogenic signaling growth factors (GFs), vascular endothelial growth factor (VEGF

Indexed as

Coculture TechniquesFibroblast Growth Factor 2Human Umbilical Vein Endothelial CellsHydrogelsTissue EngineeringAdipose TissueCell ProliferationCell SurvivalGelatinHumansIntercellular Signaling Peptides and ProteinsMethacrylatesNeovascularization, PhysiologicStem CellsVascular Endothelial Growth Factor AFibroblast Growth Factor 2GelatinHydrogelsIntercellular Signaling Peptides and ProteinsMethacrylatesVascular Endothelial Growth Factor AVEGFA protein, humanbFGFgelMAhADSCshUVECsvascular formationvEGF

Identifiers

PMID38634810
PMCPMC11094682
OpenAlexW4394914478

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.