Evidence map›Paper›PMID 38634169›Full record

ArticleEuropean journal of neurology2024

Prevalence, recovery and phenotype of dysphagia in patients with ischaemic cerebellar stroke.

Jan Hendrik Schaefer, Felix Luft, Alexander Seiler, Elena Harborth, Sara Kaffenberger, Christoph Polkowski, Christian Foerch, Sriramya Lapa

Open access · goldAbstract read
In one paragraph

Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jan Hendrik SchaeferDepartment of Neurology, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Felix LuftDepartment of Neurology, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Alexander SeilerDepartment of Neurology, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Elena HarborthDepartment of Neurology, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Sara KaffenbergerDepartment of Communication Disorders, University of Canterbury, Christchurch, New Zealand.
Christoph PolkowskiInstitute of Neuroradiology, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Christian FoerchDepartment of Neurology, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Sriramya LapaDepartment of Neurology, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany.
Goethe University Frankfurt · DEUniversity Hospital Frankfurt · DEUniversity Hospital Schleswig-Holstein · DEUniversity of Canterbury · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSwallowing is a complex task, moderated by a sophisticated bilateral network including multiple supratentorial regions, the brainstem and the cerebellum. To date, conflicting data exist about whether focal lesions to the cerebellum are associated with dysphagia. Therefore, the aim of the study was to evaluate dysphagia prevalence, recovery and dysphagia pattern in patients with ischaemic cerebellar stroke.

methodsA retrospective analysis of patients consecutively admitted to an academic stroke centre with ischaemic stroke found only in the cerebellum was performed. The presence of dysphagia was the primary end-point and was assessed by a speech-language pathologist, according to defined criteria. Dysphagia pattern was evaluated by analysing the videos of the flexible endoscopic evaluation of swallowing. Brain imaging was used to identify lesion size and location associated with dysphagia.

resultsBetween January 2016 and December 2021, 102 patients (35.3% female) with a mean age of 52.8 ± 17.3 years were included. Thirteen (12.7%) patients presented with dysphagia. The most frequently observed flexible endoscopic evaluation of swallowing phenotype was premature spillage (n = 7; 58.3%), whilst significant residues or aspiration did not occur. One patient died (7.7%); the other patients showed improvement of dysphagia and one patient (7.7%) was discharged with dietary restrictions.

conclusionsAlthough the involvement of the cerebellum in deglutition has become increasingly evident, isolated lesions to the cerebellum are less likely to cause clinically relevant and persisting dysphagia compared to other brain regions. The observed dysphagia pattern shows a lack of coordination and control, resulting in premature spillage or fragmented bolus transfer in some patients.

Indexed as

CerebellumDeglutitionDeglutition DisordersIschemic StrokeRecovery of FunctionAdultAgedFemaleHumansLaryngoscopyMaleMiddle AgedPrevalenceTomography, X-Ray ComputedaspirationcerebellumdysphagiaFEESstroke

Identifiers

PMID38634169
PMCPMC11235856
OpenAlexW4394919076

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.