Evidence map›Paper›PMID 38633909›Full record

ArticleInfectious diseases & clinical microbiology2023

CD4

Esma Eryılmaz-Eren, Mustafa Yavuz Köker, Aysegul Ulu-Kılıç, Hatice Tuna Hürmet-Öz, Yasemin Ay-Altıntop, Esma Saatçi, Sevil Özsoy, Ayşin Kılınç-Toker, Ulaş Serkan Topaloğlu, Recep Civan Yüksel and 3 more

Abstract read
In one paragraph

Article in Infectious diseases & clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Esma Eryılmaz-ErenDepartment of Infectious Diseases and Clinical Microbiology, Kayseri City Education and Research Hospital, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-2712-9694
Mustafa Yavuz KökerDepartment of Immunology, Erciyes University School of Medicine, Kayseri, Turkey.ORCID https://orcid.org/0000-0001-7061-8525
Aysegul Ulu-KılıçDepartment of Infectious Diseases and Clinical Microbiology, Erciyes University School of Medicine, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-5105-1348
Hatice Tuna Hürmet-ÖzDepartment of Medical Microbiology, Kayseri City Education and Research Hospital, Kayseri, Turkey.ORCID https://orcid.org/0000-0001-8452-0094
Yasemin Ay-AltıntopDepartment of Medical Microbiology, Kayseri City Education and Research Hospital, Kayseri, Turkey.ORCID https://orcid.org/0000-0001-6586-5561
Esma SaatçiDepartment of Medical Microbiology, Kayseri City Education and Research Hospital, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-6571-2077
Sevil ÖzsoyDepartment of Immunology, Erciyes University School of Medicine, Kayseri, Turkey.ORCID https://orcid.org/0000-0001-5998-6917
Ayşin Kılınç-TokerDepartment of Internal Medicine, Kayseri City Education and Research Hospital, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-6775-1234
Ulaş Serkan TopaloğluDepartment of Internal Medicine and Intensive Care, Erciyes University School of Medicine, Kayseri, Turkey.ORCID https://orcid.org/0000-0001-6625-7763
Recep Civan YükselDepartment of Infectious Diseases and Clinical Microbiology, Kayseri City Education and Research Hospital, Kayseri, Turkey.ORCID https://orcid.org/0000-0003-4496-9473
Hüseyin AvcılarDepartment of Immunology, Erciyes University School of Medicine, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-3871-9673
Zehra Beştepe-DursunDepartment of Infectious Diseases and Clinical Microbiology, Kayseri City Education and Research Hospital, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-6736-0380
İlhami ÇelikDepartment of Infectious Diseases and Clinical Microbiology, Kayseri City Education and Research Hospital, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-2604-3776

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Most patients with coronavirus disease (COVID-19) have abnormalities of lymphocyte subsets. This study aimed to determine the distribution of lymphocytes in patients with various severity levels of COVID-19 and to describe the relationship between the CD4 Materials and Methods: Adult (>18 years old) patients with COVID-19 who followed up in a tertiary hospital were included in the study prospectively. Demographic and clinical characteristics of the patients were obtained from the hospital records. Peripheral flow cytometry was studied in patients with different severity of COVID-19 and different prognoses. Next, we analyzed the characteristics and predictive values of lymphocyte subsets in COVID-19 patients. Results: Totally 86 patients were included in the study, of which 21 (24.4%) had asymptomatic, 23 (26.7%) had mild/moderate, and 42 (48.8%) had severe/critical COVID-19. Severe/critical patients had lower lymphocyte levels and older age than asymptomatic patients ( Conclusion: A low CD4

Indexed as

CD4+ T helperlymphocyte subsetsevere COVID-19

Identifiers

PMID38633909
PMCPMC10985810

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.