Evidence map›Paper›PMID 38633849›Full record

ArticleInfectious diseases & clinical microbiology2023

Association of Serum Krebs von den Lungen-6 (KL-6) Levels and Disease Severity in Patients Hospitalized with COVID-19.

Oğuz Evlice, Murat Bektaş, Fatih Kar, Feride Marim, İlknur Kaya, Kerem Yörükoğlu, Öznur Ak

Open access · hybridAbstract read
In one paragraph

Article in Infectious diseases & clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Oğuz EvliceDepartment of Infectious Diseases and Clinical Microbiology, Kütahya Health Sciences University School of Medicine, Kütahya, Türkiye.ORCID https://orcid.org/0000-0001-6939-0367
Murat BektaşDepartment of Romatology, İstanbul University İstanbul School of Medicine, İstanbul, Türkiye.ORCID https://orcid.org/0000-0002-1788-3837
Fatih KarDepartment of Medical Biochemistry, Kütahya Health Sciences University School of Medicine, Kütahya, Türkiye.ORCID https://orcid.org/0000-0001-8356-9806
Feride MarimDepartment of Chest Diseases, Kütahya Health Sciences University School of Medicine, Kütahya, Türkiye.ORCID https://orcid.org/0000-0002-5677-7842
İlknur KayaDepartment of Chest Diseases, Kütahya Health Sciences University School of Medicine, Kütahya, Türkiye.ORCID https://orcid.org/0000-0002-0227-9215
Kerem YörükoğluDepartments of Internal Medicine, Kütahya Health Sciences University School of Medicine, Kütahya, Türkiye.ORCID https://orcid.org/0000-0001-8741-7113
Öznur AkDepartment of Infectious Diseases and Clinical Microbiology, Kütahya Health Sciences University School of Medicine, Kütahya, Türkiye.ORCID https://orcid.org/0000-0003-3790-3070
Sağlık Bilimleri Üniversitesi · TRDumlupinar University · TRIstanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We aimed to evaluate Krebs von den Lungen-6 (KL-6) as a possible biomarker in determining disease severity in patients with moderate and severe COVID-19. Materials and Methods: This cross-sectional study included moderate or severe COVID-19 patients; critically ill patients who were followed up in the intensive care unit were not included. KL-6 level and routine laboratory test measurements were performed on the first day of admission. The patients were also categorized according to their hyperinflammatory state. Results: The study included 92 patients, 56 (61%) women. The National Institutes of Health (NIH) score was 2 in 52.2% of the patients and 3 in 47.8%. KL-6 levels did not significantly differ in disease severity (NIH score 2 vs. 3; Conclusion: There was no significant association between the serum KL-6 measured at admission and the severity of COVID-19.

Indexed as

biomarkerCOVID-19disease severityKL-6SARS-COV2

Identifiers

PMID38633849
PMCPMC10986708
OpenAlexW4390604988

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.