Evidence map›Paper›PMID 38633837›Full record

ArticleAPL bioengineering2024

Computational and experimental microfluidics: Total analysis system for mixing, sorting, and concentrating particles and cells.

David Coral, Matthew Attard, Eric Pedrol, Rosa Maria Solé, Francesc Díaz, Magdalena Aguiló, Xavier Mateos

Abstract read
In one paragraph

Article in APL bioengineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David CoralUniversity Rovira i Virgili (URV), Physics and Crystallography of Materials (FiCMA), Marcel⋅lí Domingo 1, 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0003-2561-2073
Matthew AttardUniversity Rovira i Virgili (URV), Physics and Crystallography of Materials (FiCMA), Marcel⋅lí Domingo 1, 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0001-8366-9532
Eric PedrolSRCiT - Service for Scientific and Technical Resources Campus Sescelades, N2 building, Universitat Rovira i Virgili, Països Catalans 26, Av. 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0001-9805-6990
Rosa Maria SoléUniversity Rovira i Virgili (URV), Physics and Crystallography of Materials (FiCMA), Marcel⋅lí Domingo 1, 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0002-5769-4141
Francesc DíazUniversity Rovira i Virgili (URV), Physics and Crystallography of Materials (FiCMA), Marcel⋅lí Domingo 1, 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0003-4581-4967
Magdalena AguilóUniversity Rovira i Virgili (URV), Physics and Crystallography of Materials (FiCMA), Marcel⋅lí Domingo 1, 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0001-6130-9579
Xavier MateosUniversity Rovira i Virgili (URV), Physics and Crystallography of Materials (FiCMA), Marcel⋅lí Domingo 1, 43007 Tarragona, Spain.ORCID https://orcid.org/0000-0003-1940-1990

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Body fluids can potentially indicate the presence of non-small cancer cells. Studying these fluids is an emerging field that could be crucial for cancer detection and monitoring treatment effectiveness. Meanwhile, the examination of fluids on a microscopic level is part of the field of microfluidics. This study focuses on the development of a total analysis system that consists of various interconnected structures that are designed to mix, classify, concentrate, and isolate particles in fluids that mimic the behavior of cancer and normal cells. Using the COMSOL Multiphysics software, the device's performance was optimized to use a pressure input of 35 kPa for water or serum and 29.4 kPa for a mixture of liquid and serum samples, which are the optimal pressure inputs. The numerical models were validated by experiments using two types of polystyrene particles, with diameters of 5 and 20

Identifiers

PMID38633837
PMCPMC11023705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.