Evidence map›Paper›PMID 38633736›Full record

ArticleHealth science reports2024

Efficacy of 400 mg albendazole against soil-transmitted helminthes among Salgy Primary School Children, Dembia district, Northwest Ethiopia, 2020. "Uncontrolled experimental study".

Adane Assefa, Demekech Damtie, Getu Abeje, Andargachew Almaw, Ayenew Berhan, Habtu Debsh, Molla Getie

Open access · goldAbstract read
In one paragraph

Article in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Adane AssefaDepartment of Medical Parasitology, College of Medical and Health Sciences University of Gondar Gondar Ethiopia.
Demekech DamtieDepartment of Medical Parasitology, College of Medical and Health Sciences University of Gondar Gondar Ethiopia.
Getu AbejeDepartment of Biomedical sciences, College of Medical and Health Sciences Samara University Samara Ethiopia.ORCID 0000-0003-1624-3464
Andargachew AlmawDepartment of Medical Laboratory Sciences, College of Medical and Health Sciences Debre Tabor University Debre Tabor Ethiopia.ORCID 0000-0002-4895-3017
Ayenew BerhanDepartment of Medical Laboratory Sciences, College of Medical and Health Sciences Debre Tabor University Debre Tabor Ethiopia.
Habtu DebshDepartment of Medical Laboratory Sciences, College of Medical and Health Sciences Wollo University Dessie Ethiopia.ORCID 0000-0003-2512-4897
Molla GetieDepartment of Medical Laboratory Sciences, College of Medical and Health Sciences Inji-bara University inje-bara Ethiopia.
Debre Tabor University · ETUniversity of Gondar · ETSamara University · ETSir Sayajirao General Hospital Medical College · INWollo University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Soil-transmitted helminths are one of the most prevalent causes of both intellectual and physical disability in the world. Albendazole (ALB) is a drug recommended for mass treatment of the high burden of soil-transmitted helminths in schoolchildren, particularly in developing countries. However, some researchers have reported that the efficacy of albedazole against soil-transmitted helminths is inconsistent. Monitoring the programs is crucial to evaluating the effectiveness of 400 mg of ALB against soil-transmitted helminths, as well as any changes in its therapeutic efficacy. Thus, the purpose of this study was to evaluate ALB effectiveness in treating soil-transmitted helminthes in Salgy Primary School Children. Methods: An uncontrolled experimental study was conducted at Salgy Primary School Children, Northwest Ethiopia, from March to May 2020. A total of 439 schoolchildren were enrolled and screened for soil-transmitted helminths by stratified proportionate systematic random sampling to get 228 positive schoolchildren. Students in grades one through eight were grouped based on their educational attainment. Using the Kato-Katz thick smear technique, the selected stool sample collected from school children was examined using the Kato-Katz thick smear technique to determine the cure and egg reduction rates. The statistical package for social science software, version 20, was used to analyze the data. To determine the relationship between CR (cure rate) and ERR (egg reduction rate) by age, a chi-square test ( Results: A 400 mg single dosage of ALB showed a 99.35% CR and a 97.30% egg reduction rate against Conclusion: A single dose of 400 mg ALB is effective (satisfactory), doubtful, and unsatisfactory against

Indexed as

albendazolecure rateegg reduction rateEthiopiasoil‐transmitted helminths

Identifiers

PMID38633736
PMCPMC11022293
OpenAlexW4394893580

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.