Evidence map›Paper›PMID 38633534›Full record

ArticleFrontiers in neurology2024

Dysexecutive difficulty and subtle everyday functional disabilities: the digital Trail Making Test.

David J Libon, Rod Swenson, Sean Tobyne, Ali Jannati, Daniel Schulman, Catherine C Price, Melissa Lamar, Alvaro Pascual-Leone

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

David J LibonDepartment of Geriatrics and Gerontology, New Institute for Successful Aging, Rowan University-School of Osteopathic Medicine, Stratford, NJ, United States.
Rod SwensonUniversity of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, United States.
Sean TobyneLinus Health, Boston, MA, United States.
Ali JannatiLinus Health, Boston, MA, United States.
Daniel SchulmanLinus Health, Boston, MA, United States.
Catherine C PriceDepartment of Clinical and Health Psychology, University of Florida, Gainesville, FL, United States.
Melissa LamarRush Alzheimer's Disease Center and the Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States.
Alvaro Pascual-LeoneLinus Health, Boston, MA, United States.
Christus Health · USHebrew SeniorLife · USRowan University · USRush University Medical Center · USUniversity of Florida Health · USUniversity of North Dakota · US

Funding

PRECEDE: PREsurgical Cognitive Evaluation via Digital clockfacEdrawingR01AG055337 · NIA · UNIVERSITY OF FLORIDA · PI CATHERINE E PRICE, Parisa Rashidi · 2017 to 2026
$3.2M
NIA NIH HHS R01 AG055337
6 · The paper itself

Abstract

Background: Digital neuropsychological tests reliably capture real-time, process-based behavior that traditional paper/pencil tests cannot detect, enabling earlier detection of neurodegenerative illness. We assessed relations between informant-based subtle and mild functional decline and process-based features extracted from the digital Trail Making Test-Part B (dTMT-B). Methods: A total of 321 community-dwelling participants (56.0% female) were assessed with the Functional Activities Questionnaire (FAQ) and the dTMT-B. Three FAQ groups were constructed: FAQ = 0 (unimpaired); FAQ = 1-4 (subtle impairment); FAQ = 5-8 (mild impairment). Results: Compared to the FAQ-unimpaired group, other groups required longer pauses inside target circles ( Conclusion: Digital assessment technology elegantly quantifies occult, nuanced behavior not previously appreciated, operationally defines critical underlying neurocognitive constructs related to functional abilities, and yields selected process-based scores that outperform traditional paper/pencil test scores for participant classification. When brought to scale, the dTMT-B test could be a sensitive tool to detect subtle-to-mild functional deficits in emergent neurodegenerative illnesses.

Indexed as

Boston process approachexecutive controlIADL abilitiesmild cognitive impairmentsubtle cognitive impairmentTrail Making Test-Part B

Identifiers

PMID38633534
PMCPMC11021769
OpenAlexW4393866615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.