Evidence map›Paper›PMID 38633390›Full record

ArticleInfectious diseases & clinical microbiology2022

Cognitive Assessment of Young Adults Before and After Initiation of Combination Antiretroviral Therapy.

Özlem Gül, Alper Gündüz, Dilek Yıldız Sevgi, Nazife Duygu Demirbaş, Nuray Uzun, İlyas Dökmetaş

Abstract read
In one paragraph

Article in Infectious diseases & clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Özlem GülInfectious Disease and Clinical Microbiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Türkiye.ORCID https://orcid.org/0000-0002-1668-0157
Alper GündüzInfectious Disease and Clinical Microbiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Türkiye.ORCID https://orcid.org/0000-0001-9154-844X
Dilek Yıldız SevgiInfectious Disease and Clinical Microbiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Türkiye.ORCID https://orcid.org/0000-0002-6047-4879
Nazife Duygu DemirbaşInfectious Disease and Clinical Microbiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Türkiye.ORCID https://orcid.org/0000-0002-0760-7740
Nuray UzunInfectious Disease and Clinical Microbiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Türkiye.ORCID https://orcid.org/0000-0002-3582-9551
İlyas DökmetaşInfectious Disease and Clinical Microbiology, Şişli Hamidiye Etfal Training and Research Hospital, İstanbul, Türkiye.ORCID https://orcid.org/0000-0003-3523-3923

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In the determination and monitoring of neurocognitive disorders in human immunodeficiency virus (HIV)-positive individuals, there is a need for significantly more practical methods which provide results in a shorter time than the tests that require challenging and specialized expertise. This study aimed to evaluate cognitive functions and the factors affecting them in naïve HIV-positive patients using by Montreal Cognitive Assessment (MoCA) test before and after the initiation of combination antiretroviral therapy. Materials and Methods: HIV-positive, treatment-naïve patients monitored between January-June 2017 were included in the study. The MoCA test was performed at the beginning and the sixth month of the treatment. Results: Forty male patients were included in the study. The mean age was calculated as 29.1±4.0. When the factors affecting the MoCA score were examined, there was a significant relationship between the education level and the MoCA score. Smoking, using alcohol, and substance did not have a significant impact on baseline MoCA values. A significant correlation was found between cluster differentiation 4 (CD4) count and HIV RNA level and attention function. There was a significant increase in the total MoCA score and the MoCA subgroup scores at the end of the sixth month of the treatment. Conclusion: MoCA test is one of the most practical tests that can be applied in a short time period, and it was found useful in evaluating the changes in the cognitive functions of HIV-positive patients during antiretroviral treatment.

Indexed as

antiretroviral treatmentcognitive functionsHIVMoCA testneurocognitive disorders

Identifiers

PMID38633390
PMCPMC10986713

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.