Evidence map›Paper›PMID 38633153›Full record

ArticleOpen veterinary journal2024

Immunological effects of ractopamine in rabbits receiving the viral inactivated rabbit hemorrhagic disease vaccine.

Gamal A Shams, Hosny A Ibrahim, Heba M Hassan, Nashwa S Semary, Abeer F I Hassan

Open access · goldAbstract read
In one paragraph

Article in Open veterinary journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gamal A ShamsDepartment of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
Hosny A IbrahimDepartment of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
Heba M HassanAnimal Health Research Institute (AHRI), Agriculture Research Center (ARC), Giza, Egypt.
Nashwa S SemaryAnimal Health Research Institute (AHRI), Agriculture Research Center (ARC), Zagazig, Egypt.
Abeer F I HassanEducational Veterinary Hospital, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
Zagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is an obvious lack of information about the effects of ractopamine, a ß-adrenergic agonist, on the growth performance and immune responses of rabbits, particularly in those receiving the viral rabbit hemorrhagic disease (RHD) vaccine. Aim: The current study was undertaken to study the effects of ractopamine on growth performances and immunological parameters in rabbits inoculated with the viral RHD vaccine. Methods: Experimental rabbits were grouped into four groups, the first acted as a control and received distilled water, the second received ractopamine, the third received inactivated RHD vaccine, and the fourth received both ractopamine, and inactivated RHD vaccine. Then, blood analysis, histopathological, histomorphometric, and immunohistochemistry (IHC) examinations were followed. Results: The obtained results demonstrated that ractopamine induced significant increases in body weight gain, neutrophils, monocytes, nitric oxide, lysosome, and improved feed conversion rate. A significant decrease in lymphocytes with insignificant decreases in eosinophils, phagocytic % and index, serum total protein, Conclusion: Ractopamine induced several adverse effects on the immune responses of the rabbits inoculated with the viral HRD vaccine.

Indexed as

Nitric OxidePhenethylaminesViral VaccinesAnimalsAntibodies, ViralBody WeightCaspase 3gamma-GlobulinsVaccines, InactivatedWeight GainAntibodies, ViralCaspase 3gamma-GlobulinsNitric OxidePhenethylaminesractopamineVaccines, InactivatedViral VaccinesImmunityRabbit hemorrhagic virus vaccineRabbitsRactopamineViral diseases

Identifiers

PMID38633153
PMCPMC11018428
OpenAlexW4391581072

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.