Evidence map›Paper›PMID 38633037›Full record

ReviewNanoscale advances2024

Nanotechnology-enabled sonodynamic therapy against malignant tumors.

Yunxi Huang, Wenhao Ouyang, Zijia Lai, Guanhua Qiu, Zhaoting Bu, Xiaoqi Zhu, Qin Wang, Yunfang Yu, Junjie Liu

Abstract readReview
In one paragraph

Review in Nanoscale advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
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  6. Review
  7. Article
  8. External Stimuli-Activable Single-Atom Nanozymes for Bioapplications.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. AnIranian journal of basic medical sciences · 2026
    Article
  15. Article
  16. Review
  17. Article
  18. BaTiOPharmaceutics · 2025
    Review
  19. Article
  20. Harnessing Ultrasonic Technologies to TreatMolecules (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yunxi HuangDepartment of Medical Ultrasound, Guangxi Medical University Cancer Hospital 77 He Di Road 530021 Nanning China liujunjie197806@163.com.
Wenhao OuyangGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Medical Oncology, Yat-sen Supercomputer Intelligent Medical Joint Research Institute, Phase I Clinical Trial Centre, Sun Yat-sen Memorial Hospital, Sun Yat-sen University 510120 Guangzhou China yuyf9@mail.sysu.edu.cn.
Zijia LaiFirst Clinical Medical College, Guangdong Medical University 524000 Zhanjiang China.
Guanhua QiuDepartment of Medical Ultrasound, Guangxi Medical University Cancer Hospital 77 He Di Road 530021 Nanning China liujunjie197806@163.com.
Zhaoting BuDepartment of Medical Ultrasound, Guangxi Medical University Cancer Hospital 77 He Di Road 530021 Nanning China liujunjie197806@163.com.
Xiaoqi ZhuDepartment of Medical Ultrasound, Guangxi Medical University Cancer Hospital 77 He Di Road 530021 Nanning China liujunjie197806@163.com.
Qin WangDepartment of Medical Ultrasound, Guangxi Medical University Cancer Hospital 77 He Di Road 530021 Nanning China liujunjie197806@163.com.
Yunfang YuGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Medical Oncology, Yat-sen Supercomputer Intelligent Medical Joint Research Institute, Phase I Clinical Trial Centre, Sun Yat-sen Memorial Hospital, Sun Yat-sen University 510120 Guangzhou China yuyf9@mail.sysu.edu.cn.ORCID https://orcid.org/0000-0003-2579-6220
Junjie LiuDepartment of Medical Ultrasound, Guangxi Medical University Cancer Hospital 77 He Di Road 530021 Nanning China liujunjie197806@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sonodynamic therapy (SDT) is an emerging approach for malignant tumor treatment, offering high precision, deep tissue penetration, and minimal side effects. The rapid advancements in nanotechnology, particularly in cancer treatment, have enhanced the efficacy and targeting specificity of SDT. Combining sonodynamic therapy with nanotechnology offers a promising direction for future cancer treatments. In this review, we first systematically discussed the anti-tumor mechanism of SDT and then summarized the common nanotechnology-related sonosensitizers and their recent applications. Subsequently, nanotechnology-related therapies derived using the SDT mechanism were elaborated. Finally, the role of nanomaterials in SDT combined therapy was also introduced.

Identifiers

PMID38633037
PMCPMC11019498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.