Evidence map›Paper›PMID 38633006›Full record

ArticleInfectious diseases & clinical microbiology2023

Hypochlorous Acid: A Novel Agent Against

Oruç Numan Gökçe, Kenan Çetin, Şükrü Taş, Sevil Alkan, Uğur Dinç

Abstract read
In one paragraph

Article in Infectious diseases & clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oruç Numan GökçeDepartment of General Surgery, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Turkey.ORCID https://orcid.org/0000-0002-9678-7818
Kenan ÇetinDepartment of General Surgery, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Turkey.ORCID https://orcid.org/0000-0002-8616-9784
Şükrü TaşDepartment of General Surgery, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Turkey.ORCID https://orcid.org/0000-0001-6178-7546
Sevil AlkanDepartment of Infectious Disease and Clinical Microbiology, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Turkey.ORCID https://orcid.org/0000-0003-1944-2477
Uğur DinçDepartment of Public Health, Çanakkale Public Health Laboratory, Ministery of Health Çanakkale, Turkey.ORCID https://orcid.org/0000-0002-4414-663X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We aimed to determine the scolicidal effect of hypochlorous acid and its efficiency at different concentrations. Materials and Methods: We tested the effectiveness of hypochlorous acid in-vitro on sterile gauze at different concentrations in test tubes. In addition, we compared its effectiveness with the scolicidal activity of other agents, povidone-iodine 10% and chlorhexidine-gluconate 0.04%. Results: Hypochlorous acid was 100% effective in 5 minutes at 1/1 (200 ppm/mL), 1/10 (20 ppm/ml), and 1/100 (2 ppm/mL) concentrations and in 10 minutes at 1/1000 (0.2 ppm/mL) concentration. Povidone-iodine 10%, and chlorhexidine-gluconate 0.04% were studied undiluted and were effective at all study times. Hypochlorous acid maintained the same scolicidal activity on gauze at all study times at the described dilutions. Conclusion: Hypochlorous acid is an effective scolicidal agent in 5 minutes at even 1/100 concentrations. In addition, it maintains the same scolicidal activity on gauze used in surgery to wall the surgical site.

Indexed as

Echinococcus granulosushydatid diseasehypochlorous acidnovelscolicidal

Identifiers

PMID38633006
PMCPMC10985818

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.