Evidence map›Paper›PMID 38632848›Full record

ArticleJournal of the International AIDS Society2024

Injection network drivers of HIV prevention service utilization among people who inject drugs: results of a community-based sociometric network cohort in New Delhi, India.

Neia S Prata Menezes, Shruti H Mehta, Amy Wesolowski, Steven J Clipman, Aylur K Srikrishnan, Muniratnam S Kumar, Katie J C Zook, Gregory M Lucas, Carl Latkin, Sunil S Solomon

Abstract read
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Article in Journal of the International AIDS Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Neia S Prata MenezesDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0001-9597-7348
Shruti H MehtaDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.
Amy WesolowskiDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.
Steven J ClipmanDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-2366-8420
Aylur K SrikrishnanYR Gaitonde Centre for AIDS Research and Education, Chennai, India.
Muniratnam S KumarYR Gaitonde Centre for AIDS Research and Education, Chennai, India.
Katie J C ZookDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Gregory M LucasDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-3013-4339
Carl LatkinDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-7931-2116
Sunil S SolomonDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Funding

TRAINEESHIPS IN AIDS PREVENTION STUDIEST32MH019105 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Carol Suzanne Camlin, Glenn-Milo Santos · 1989 to 2026
$15.3M
Strategies to improve the HIV care continuum among key populations in IndiaR01DA041034 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M, MEHTA, SHRUTI H · 2015 to 2021
$6.7M
Johns Hopkins HIV Epidemiology and Prevention Sciences Training ProgramT32AI102623 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Shruti H Mehta · 2013 to 2026
$5.3M
Individual, Network and Spatial Drivers of HIV and HCV among PWID in IndiaR01DA041736 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SOLOMON, SUNIL SUHAS · 2016 to 2021
$5.0M
Reaching the hardest of the hard-to-reachDP2DA040244 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SOLOMON, SUNIL SUHAS · 2016 to 2023
$2.8M
Molecular Networks and Deep Learning for Targeted HIV Interventions among PWIDDP2DA056130 · NIDA · JOHNS HOPKINS UNIVERSITY · PI CLIPMAN, STEVEN J. · 2022 to 2022
$2.5M
Treatment outcomes and comorbidity in HIV-infected IDUK24DA035684 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M · 2014 to 2024
$1.5M
NIAID NIH HHS T32 AI102623NIDA NIH HHS DP2 DA040244NIDA NIH HHS DP2 DA056130NIDA NIH HHS K24 DA035684NIDA NIH HHS L60 DA056996NIDA NIH HHS R01 DA041034NIDA NIH HHS R01 DA041736NIH HHS DP2DA040244NIH HHS DP2DA056130NIH HHS K24DA035684NIH HHS R01DA041034NIH HHS R01DA041736NIH HHS T32AI102623NIMH NIH HHS T32 MH019105
6 · The paper itself

Abstract

introductionInjection drug networks may influence their network members' health-seeking behaviours. Using data from a sociometric injecting partner network of people who inject drugs (PWID) in New Delhi, India, we assessed the role of injecting partner (alter) behaviours on individual engagement in HIV prevention services.

methodsWe enumerated injecting partner linkages among 2512 PWID using coupon referrals and biometric data from November 2017 to March 2020. Participants completed interviewer-administered questionnaires and provided information on injection behaviours, injecting partners, HIV/hepatitis C (HCV) testing and service engagement. Multilevel multiple-membership models (MMMM) evaluated individual PWID HIV testing, medication for opioid use disorder (MOUD) and syringe service engagement as a function of alter attributes, accounting for membership across multiple ego-networks. Logistic regression models assessed parallel associations among socially proximal injecting peers, defined as PWID ≤3 path length from ego.

resultsMedian age was 26 years; 99% were male. PWID had median 2 injecting partners and 8 socially proximal peers; 14% reported HIV testing, 33% accessed MOUD and 13% used syringe services 6 months prior. In MMMM analyses, PWID with ≥1 versus 0 injecting partners who received HIV testing were significantly more likely to report HIV testing (adjusted odds ratio [aOR]: 2.27, 95% confidence interval [CI]: 1.68-3.16), MOUD (aOR: 1.99, 95% CI: 1.60-2.53) and syringe service use (aOR: 1.66, 95% CI: 1.21-2.39). We observed similar findings for individual MOUD and syringe service use. Having ≥1 versus 0 HIV-positive partners was associated with decreased HIV testing and MOUD but increased syringe service use (aOR: 1.54, 95% CI: 1.09-2.17). PWID with ≥1 versus 0 socially proximal peers who used non-sterile injection equipment reported increased HIV testing (aOR: 1.39, 95% CI: 1.01-1.92), MOUD (aOR: 1.40, 95% CI: 1.10-1.77) and syringe service use (aOR: 1.82, 95% CI: 1.23-2.68).

conclusionsWe found differential associative relationships between individual HIV prevention service engagement and the health or risk behaviours of direct and indirect alters. Characterizing network exposure beyond direct injecting partnerships provided important context on possible mechanisms of behavioural influence. Findings could be leveraged to design peer-based interventions that promote network diffusion of health-seeking behaviours.

Indexed as

Drug UsersHepatitis CHIV InfectionsOpioid-Related DisordersSubstance Abuse, IntravenousAdultCommunity Health ServicesFemaleHumansMaledrug useharm reductionHIV preventionHIV testinginjection networkLMIC

Identifiers

PMID38632848
PMCPMC11024448

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.