Evidence map›Paper›PMID 38632311›Full record

ArticleNature communications2024

Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection.

Chansavath Phetsouphanh, Brendan Jacka, Sara Ballouz, Katherine J L Jackson, Daniel B Wilson, Bikash Manandhar, Vera Klemm, Hyon-Xhi Tan, Adam Wheatley, Anupriya Aggarwal and 12 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 37 citations in OpenAlex.

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  19. A pain from the nose to the head: neurological commitment during long COVID.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 1 country.

Chansavath PhetsouphanhThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia. cphetsouphanh@kirby.unsw.edu.au.ORCID http://orcid.org/0000-0001-6617-5995
Brendan JackaThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Sara BallouzGarvan Institute for Medical research, Sydney, NSW, Australia.
Katherine J L JacksonGarvan Institute for Medical research, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0002-9952-7069
Daniel B WilsonThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Bikash ManandharThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Vera KlemmThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Hyon-Xhi TanDepartment of Microbiology and Immunology, Peter Doherty Institute, University of Melbourne, Victoria, VIC, Australia.ORCID http://orcid.org/0000-0003-1064-3934
Adam WheatleyDepartment of Microbiology and Immunology, Peter Doherty Institute, University of Melbourne, Victoria, VIC, Australia.
Anupriya AggarwalThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Anouschka AkermanThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Vanessa MilogiannakisThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Mitchell StarrNSW State Reference Laboratory for HIV, St. Vincent's Centre for Applied Medical Research, Sydney, NSW, Australia.
Phillip CunninghamNSW State Reference Laboratory for HIV, St. Vincent's Centre for Applied Medical Research, Sydney, NSW, Australia.
Stuart G TurvilleThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0003-1918-5343
Stephen J KentDepartment of Microbiology and Immunology, Peter Doherty Institute, University of Melbourne, Victoria, VIC, Australia.ORCID http://orcid.org/0000-0002-8539-4891
Anthony ByrneHeart Lung Clinic, St. Vincent's Hospital Sydney and Faculty of Medicine and Health (UNSW), Sydney, NSW, Australia.
Bruce J BrewPeter Duncan Neurosciences Unit- St Vincent's Centre for Applied Medical Research, Sydney, NSW, Australia.
David R DarleySt. Vincent's Hospital, Darlinghurst, NSW, Australia.ORCID http://orcid.org/0000-0002-9721-101X
Gregory J DoreThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Anthony D Kelleher *The Kirby Institute, University of New South Wales, Sydney, NSW, Australia. akelleher@kirby.unsw.edu.au.ORCID http://orcid.org/0000-0002-0009-3337
Gail V Matthews *The Kirby Institute, University of New South Wales, Sydney, NSW, Australia. gmatthews@kirby.unsw.edu.au.
UNSW Sydney · AUThe University of Melbourne · AUGarvan Institute of Medical Research · AUSt Vincent's Hospital Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC) compared to age and gender matched recovered COVID-19 controls (MC) over 24 months. LC participants show elevated nucleocapsid IgG levels at 3 months, and higher neutralizing capacity up to 8 months post-infection. Increased spike-specific and nucleocapsid-specific CD4

Indexed as

COVID-19Post-Acute COVID-19 SyndromeAntibodies, ViralCD8-Positive T-LymphocytesHumansQuality of LifeSARS-CoV-2Antibodies, Viral

Identifiers

PMID38632311
PMCPMC11024141
OpenAlexW4394872329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.