Evidence map›Paper›PMID 38632251›Full record

SynthesisCell death & disease2024

The relationship between the network of non-coding RNAs-molecular targets and N6-methyladenosine modification in tumors of urinary system.

Ruiming Li, Chunming Zhu, Yuan Wang, Xia Wang, Yibing Wang, Jiahe Wang, Kefeng Wang

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Cell death & disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ruiming Li *Department of Urology, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
Chunming Zhu *Department of Family Medicine, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
Yuan Wang *Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
Xia WangDepartment of Urology, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
Yibing WangDepartment of Urology, Shengjing Hospital of China Medical University, Shenyang, 110004, China. yibing_wang2015@126.com.
Jiahe WangDepartment of Family Medicine, Shengjing Hospital of China Medical University, Shenyang, 110004, China. wangjiaheanglee@126.com.
Kefeng WangDepartment of Urology, Shengjing Hospital of China Medical University, Shenyang, 110004, China. wang.kefeng@hotmail.com.ORCID 0000-0003-0014-9182
China Medical University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82072835
6 · The paper itself

Abstract

N6-methyladenosine (m6A) methylation, a prevalent eukaryotic post-transcriptional modification, is involved in multiple biological functions, including mediating variable splicing, RNA maturation, transcription, and nuclear export, and also is vital for regulating RNA translation, stability, and cytoplasmic degradation. For example, m6A methylation can regulate pre-miRNA expression by affecting both splicing and maturation. Non-coding RNA (ncRNA), which includes microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), does not encode proteins but has powerful impacts on transcription and translation. Conversely, ncRNAs may impact m6A methylation by affecting the expression of m6A regulators, including miRNAs targeting mRNA of m6A regulators, or lncRNAs, and circRNAs, acting as scaffolds to regulate transcription of m6A regulatory factors. Dysregulation of m6A methylation is common in urinary tumors, and the regulatory role of ncRNAs is also important for these malignancies. This article provides a systematic review of the role and mechanisms of action of m6A methylation and ncRNAs in urinary tumors.

Indexed as

AdenosineRNA, UntranslatedGene Expression Regulation, NeoplasticHumansMethylationMicroRNAsRNA, CircularRNA, Long NoncodingAdenosineMicroRNAsN-methyladenosineRNA, CircularRNA, Long NoncodingRNA, Untranslated

Identifiers

PMID38632251
PMCPMC11024199
OpenAlexW4394877223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.