Evidence map›Paper›PMID 38632227›Full record

ArticleNature communications2024

MmcA is an electron conduit that facilitates both intracellular and extracellular electron transport in Methanosarcina acetivorans.

Dinesh Gupta, Keying Chen, Sean J Elliott, Dipti D Nayak

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. mBio · 2026
    Article
  3. Article
  4. Article
  5. Cell surface differences within the genusJournal of bacteriology · 2025
    Review
  6. Biochemistry · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dinesh GuptaDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-9108-9669
Keying ChenDepartment of Chemistry, Boston University, Boston, MA, USA.
Sean J ElliottDepartment of Chemistry, Boston University, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0096-9551
Dipti D NayakDepartment of Molecular and Cell Biology, University of California, Berkeley, CA, USA. dnayak@berkeley.edu.ORCID http://orcid.org/0000-0002-8390-7251
Boston University · USUniversity of California, Berkeley · US

Funding

Redox Cofactor Diversity in Enzymatic SuperfamiliesR35GM136294 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI SEAN J ELLIOTT · 2020 to 2026
$2.9M
NIGMS NIH HHS R35 GM136294
6 · The paper itself

Abstract

Methanogens are a diverse group of Archaea that obligately couple energy conservation to the production of methane. Some methanogens encode alternate pathways for energy conservation, like anaerobic respiration, but the biochemical details of this process are unknown. We show that a multiheme c-type cytochrome called MmcA from Methanosarcina acetivorans is important for intracellular electron transport during methanogenesis and can also reduce extracellular electron acceptors like soluble Fe

Indexed as

ElectronsMethanosarcinaCytochromesElectron TransportMethaneOxidation-ReductionCytochromesMethane

Identifiers

PMID38632227
PMCPMC11024163
OpenAlexW4394880850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.