Evidence map›Paper›PMID 38632144›Full record

ArticleEuropean journal of nutrition2024

Meat consumption and the risk of hip fracture in women and men: two prospective Swedish cohort studies.

Eva Warensjö Lemming, Liisa Byberg, Jonas Höijer, John A Baron, Alicja Wolk, Karl Michaëlsson

Open access · hybridAbstract read
In one paragraph

Article in European journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Eva Warensjö LemmingMedical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala Science Park, MTC/Epihubben, Dag Hammarskjölds väg 14B, 751 83, Uppsala, Sweden. eva.warensjo.lemming@uu.se.ORCID http://orcid.org/0000-0002-0149-452X
Liisa BybergMedical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala Science Park, MTC/Epihubben, Dag Hammarskjölds väg 14B, 751 83, Uppsala, Sweden.
Jonas HöijerMedical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala Science Park, MTC/Epihubben, Dag Hammarskjölds väg 14B, 751 83, Uppsala, Sweden.
John A BaronMedical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala Science Park, MTC/Epihubben, Dag Hammarskjölds väg 14B, 751 83, Uppsala, Sweden.
Alicja WolkUnit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Karl MichaëlssonMedical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala Science Park, MTC/Epihubben, Dag Hammarskjölds väg 14B, 751 83, Uppsala, Sweden.
Uppsala University · SEKarolinska Institutet · SEUniversity of North Carolina at Chapel Hill · US

Funding

Vetenskapsrådet Several
6 · The paper itself

Abstract

purposeTo study the association between meat intake (predominantly red and processed meats) and the risk of hip fracture, as well as the association between meat intake and biomarkers of inflammation, oxidative stress, bone turnover, body composition, and bone mineral density (BMD).

methodsData from the Swedish Mammography Cohort and the Cohort of Swedish men (n = 83,603, 54% men) with repeated investigations and their respective clinical sub-cohorts was utilised. Incident hip fractures were ascertained through individual linkage to registers. Associations were investigated using multivariable Cox and linear regression analyses.

resultsDuring up to 23 years of follow-up (mean 18.2 years) and 1,538,627 person-years at risk, 7345 participants (2840 men) experienced a hip fracture. Each daily serving of meat intake conferred a hazard ratio (HR) of 1.03 (95% confidence interval [CI] 1.00; 1.06) for hip fracture. In quintile 5, compared to quintile 2, the HR was 1.11 (95% CI 1.01; 1.21) among all participants. In the sub-cohorts, meat intake was directly associated with circulating levels of interleukin-6, C-reactive protein, leptin, ferritin, parathyroid hormone, and calcium.

conclusionA modest linear association was found between a higher meat intake and the risk of hip fractures. Our results from the sub-cohorts further suggest that possible mechanisms linking meat intake and hip fracture risk may be related to the regulation of bone turnover, subclinical inflammation, and oxidative stress. Although estimates are modest, limiting red and processed meat intake in a healthy diet is advisable to prevent hip fractures.

Indexed as

BiomarkersHip FracturesMeatAgedBody CompositionBone DensityCohort StudiesC-Reactive ProteinDietFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedOxidative StressBiomarkersC-Reactive ProteinBiomarkersBone turnoverCohortHip fractureMeat intake

Identifiers

PMID38632144
PMCPMC11329405
OpenAlexW4394872460

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.