Evidence map›Paper›PMID 38631596›Full record

ArticleBone2024

More accurate trabecular bone imaging using UTE MRI at the resonance frequency of fat.

Saeed Jerban, Dina Moazamian, Hamidreza Shaterian Mohammadi, Yajun Ma, Hyungseok Jang, Behnam Namiranian, Soo Hyun Shin, Salem Alenezi, Sameer B Shah, Christine B Chung and 2 more

Open access · greenAbstract read
In one paragraph

Article in Bone, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Saeed JerbanDepartment of Radiology, University of California, San Diego, La Jolla, CA, USA. Electronic address: sjerban@health.ucsd.edu.
Dina MoazamianDepartment of Radiology, University of California, San Diego, La Jolla, CA, USA.
Hamidreza Shaterian MohammadiDepartment of Radiology, University of California, San Diego, La Jolla, CA, USA.
Yajun MaDepartment of Radiology, University of California, San Diego, La Jolla, CA, USA.
Hyungseok JangDepartment of Radiology, University of California, San Diego, La Jolla, CA, USA.
Behnam NamiranianDepartment of Radiology, University of California, San Diego, La Jolla, CA, USA.
Soo Hyun ShinDepartment of Radiology, University of California, San Diego, La Jolla, CA, USA.
Salem AleneziResearch and Laboratories Sector, Saudi Food and Drug Authority, Riyadh, Saudi Arabia.
Sameer B ShahRadiology Service, Veterans Affairs San Diego Healthcare System, San Diego, La Jolla, CA, USA; Orthopaedic Research, University of California, San Diego, La Jolla, CA, USA.
Christine B ChungDepartment of Radiology, University of California, San Diego, La Jolla, CA, USA; Radiology Service, Veterans Affairs San Diego Healthcare System, San Diego, La Jolla, CA, USA.
Eric Y ChangDepartment of Radiology, University of California, San Diego, La Jolla, CA, USA; Radiology Service, Veterans Affairs San Diego Healthcare System, San Diego, La Jolla, CA, USA.
Jiang DuDepartment of Radiology, University of California, San Diego, La Jolla, CA, USA; Radiology Service, Veterans Affairs San Diego Healthcare System, San Diego, La Jolla, CA, USA. Electronic address: jiangdu@health.ucsd.edu.
University of California, San Diego · USSaudi Arabian Monetary Authority · SAVA San Diego Healthcare System · US

Funding

Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of BoneR01AR068987 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2015 to 2024
$4.9M
Quantitative UTE MR Imaging: Sensitive Biomarkers for OsteoarthritisR01AR062581 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2013 to 2022
$4.1M
Resource-based Center for the study of the joint microenvironment in rheumatology (Overall Application)P30AR073761 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CORR, MARY P · 2018 to 2022
$3.9M
Ultrashort Echo Time Magnetic Resonance Imaging of the Lumbar Intervertebral Disc.R01AR079484 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Yajun Ma · 2022 to 2026
$2.7M
Ultrashort Echo Time Magnetic Resonance Imaging of Hemophilic ArthropathyR01AR078877 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JANG, HYUNGSEOK · 2021 to 2025
$2.4M
Three-dimensional Ultrashort Echo Time Magnetic Resonance Imaging of EnthesesR01AR075825 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI CHANG, ERIC Y · 2019 to 2023
$1.8M
Knee evaluation under mechanical loading by cones ultrashort echo time MR imagingK01AR080257 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI saeed jerban · 2022 to 2026
$602k
Multi-scale MRI Assessment of Bone Quality and Function in a Chronic Rat Spinal Cord Injury ModelI01BX005952 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI Eric Y Chang · 2023 to 2026
–
Ultrashort TE MR Imaging of Femorotibial CartilageI01CX000625 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHRISTINE B CHUNG · 2012 to 2026
–
Medical Imaging of Peripheral Nerve Injury and RepairI01CX002118 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI Sameer B. Shah · 2021 to 2026
–
Quantitative Magnetic Resonance Imaging of Human Rotator Cuff TendonI01CX001388 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2016 to 2024
–
BLRD VA I01 BX005952CSRD VA I01 CX000625CSRD VA I01 CX001388CSRD VA I01 CX002118NIAMS NIH HHS K01 AR080257NIAMS NIH HHS P30 AR073761NIAMS NIH HHS R01 AR062581NIAMS NIH HHS R01 AR068987NIAMS NIH HHS R01 AR075825NIAMS NIH HHS R01 AR078877NIAMS NIH HHS R01 AR079484
6 · The paper itself

Abstract

High-resolution magnetic resonance imaging (HR-MRI) has been increasingly used to assess the trabecular bone structure. High susceptibility at the marrow/bone interface may significantly reduce the marrow's apparent transverse relaxation time (T2*), overestimating trabecular bone thickness. Ultrashort echo time MRI (UTE-MRI) can minimize the signal loss caused by susceptibility-induced T2* shortening. However, UTE-MRI is sensitive to chemical shift artifacts, which manifest as spatial blurring and ringing artifacts partially due to non-Cartesian sampling. In this study, we proposed UTE-MRI at the resonance frequency of fat to minimize marrow-related chemical shift artifacts and the overestimation of trabecular thickness. Cubes of trabecular bone from six donors (75 ± 4 years old) were scanned using a 3 T clinical scanner at the resonance frequencies of fat and water, respectively, using 3D UTE sequences with five TEs (0.032, 1.1, 2.2, 3.3, and 4.4 ms) and a clinical 3D gradient echo (GRE) sequence at 0.2 × 0.2 × 0.4 mm

Indexed as

Cancellous BoneMagnetic Resonance ImagingAdipose TissueAgedFemaleHumansMaleFat peak frequencyMicrostructureMRITrabecular boneUTE

Identifiers

PMID38631596
PMCPMC11357721
OpenAlexW4394806041

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.