Evidence map›Paper›PMID 38631438›Full record

ArticleAnnals of epidemiology2024

Adjustment for duration of employment in occupational epidemiology.

Yeji Ko, Sara C Howard, Ashley P Golden, Benjamin French

Abstract read
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Article in Annals of epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Yeji KoDepartment of Biostatistics, Vanderbilt University Medical Center, 2525 West End Avenue Suite 1100, Nashville, TN 37203, USA.
Sara C HowardOak Ridge Associated Universities, 100 Orau Way, Oak Ridge, TN 37830, USA.
Ashley P GoldenOak Ridge Associated Universities, 100 Orau Way, Oak Ridge, TN 37830, USA.
Benjamin FrenchDepartment of Biostatistics, Vanderbilt University Medical Center, 2525 West End Avenue Suite 1100, Nashville, TN 37203, USA. Electronic address: b.french@vumc.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn occupational epidemiology, the healthy worker survivor effect can manifest as a time-dependent confounder because healthier workers can accrue greater amounts of exposure over longer periods of employment. For example, in occupational studies of radiation exposure that focus on cumulative annualized radiation dose, workers can accrue greater amounts of cumulative radiation exposure over longer periods of employment, while workers with longer periods of employment can transition into jobs with a reduced potential for annualized radiation exposure. The extent to which confounding arising from the healthy worker survivor effect impacts radiation risk estimates is unknown.

methodsWe assessed the impact of the healthy worker survivor effect on estimates of radiation risk among nuclear workers in a Million Person Study cohort. In simulation studies, we contrasted the ability of marginal structural Cox models with inverse probability weighting and Cox proportional hazards models to account for time-dependent confounding arising from the healthy worker survivor effect.

resultsMarginal structural Cox models and Cox proportional hazards models with flexible functional forms for duration of employment provided reliable results.

conclusionsIt is crucial to flexibly adjust for duration of employment to account for confounding arising from the healthy worker survivor effect in occupational epidemiology.

Indexed as

EmploymentOccupational ExposureProportional Hazards ModelsAdultCohort StudiesConfounding Factors, EpidemiologicFemaleHealthy Worker EffectHumansMaleMiddle AgedTime FactorsHealthy worker effectOccupational healthRadiationSurvival analysis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.