Evidence map›Paper›PMID 38630590›Full record

ArticleCell reports2024

Altered GM1 catabolism affects NMDAR-mediated Ca

Jason A Weesner, Ida Annunziata, Diantha van de Vlekkert, Camenzind G Robinson, Yvan Campos, Ashutosh Mishra, Leigh E Fremuth, Elida Gomero, Huimin Hu, Alessandra d'Azzo

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jason A WeesnerSt. Jude Children's Research Hospital, Department of Genetics, Memphis, TN 38105, USA.
Ida AnnunziataSt. Jude Children's Research Hospital, Department of Genetics, Memphis, TN 38105, USA; St. Jude Children's Research Hospital, Compliance Office, Memphis, TN 38105, USA.
Diantha van de VlekkertSt. Jude Children's Research Hospital, Department of Genetics, Memphis, TN 38105, USA.
Camenzind G RobinsonSt. Jude Children's Research Hospital, Cellular Imaging Shared Resource, Memphis, TN 38105, USA.
Yvan CamposSt. Jude Children's Research Hospital, Department of Genetics, Memphis, TN 38105, USA.
Ashutosh MishraSt. Jude Children's Research Hospital, Center for Proteomics and Metabolomics, Memphis, TN 38105, USA.
Leigh E FremuthSt. Jude Children's Research Hospital, Department of Genetics, Memphis, TN 38105, USA.
Elida GomeroSt. Jude Children's Research Hospital, Department of Genetics, Memphis, TN 38105, USA.
Huimin HuSt. Jude Children's Research Hospital, Department of Genetics, Memphis, TN 38105, USA.
Alessandra d'AzzoSt. Jude Children's Research Hospital, Department of Genetics, Memphis, TN 38105, USA; University of Tennessee Health Science Center, Department of Anatomy and Physiology, Memphis, TN 38163, USA. Electronic address: sandra.dazzo@stjude.org.
St. Jude Children's Research Hospital · USUniversity of Tennessee Health Science Center · US

Funding

GM1 as apoptotic signal in neurodegenerative GM1-gangliosidosisR01DK052025 · NIDDK · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI D'AZZO, ALESSANDRA · 1997 to 2010
$1.8M
FUNCTIONAL ROLES AND MECHANISMS OF SNO-RNAS IN PRE-RRNA PROCESSINGZ01DK052025 · NIDDK · DIABETES, DIGESTIVE, KIDNEY DISEASES · PI PECULIS, BRENDA A · 1996 to 2003
–
Intramural NIH HHS Z01 DK052025NIDDK NIH HHS R01 DK052025
6 · The paper itself

Abstract

Endoplasmic reticulum-plasma membrane (ER-PM) junctions mediate Ca

Indexed as

Calcium SignalingEndoplasmic ReticulumGangliosidosis, GM1G(M1) GangliosideReceptors, N-Methyl-D-AspartateAnimalsCalciumCell MembraneDendritic SpinesDisease Models, AnimalFemaleHumansMaleMiceNeuronal PlasticityNeuronsCalciumG(M1) GangliosideReceptors, N-Methyl-D-AspartateCa(2+) signalingCP: Cell biologyCP: Neurosciencedendritic spinesER-PM junctionsGM1-gangliosidosislysosomal storage diseasemembrane contact sitesNMDARsynapse

Identifiers

PMID38630590
PMCPMC11244331
OpenAlexW4394844460

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.