Evidence map›Paper›PMID 38630434›Full record

ReviewBiochemical Society transactions2024

Inorganic polyphosphate and ion transport across biological membranes.

Yaw Akosah, Jingyi Yang, Evgeny Pavlov

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biochemical Society transactions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. The roles and synthesis of inorganic polyphosphate inbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yaw AkosahDepartment of Molecular Pathobiology, New York University, New York, NY, U.S.A.ORCID 0000-0001-8222-7812
Jingyi YangDepartment of Molecular Pathobiology, New York University, New York, NY, U.S.A.
Evgeny PavlovDepartment of Molecular Pathobiology, New York University, New York, NY, U.S.A.ORCID 0000-0001-9610-9577
New York University · US

Funding

Molecular mechanisms of the mitochondrial permeability transitionR35GM139615 · NIGMS · NEW YORK UNIVERSITY · PI PAVLOV, EVGENY · 2021 to 2025
$2.3M
NIGMS NIH HHS R35 GM139615
6 · The paper itself

Abstract

Inorganic polyphosphate (polyP) is widely recognized for playing important roles and processes involved in energy and phosphate storage, regulation of gene expression, and calcium signaling. The less well-known role of polyP is as a direct mediator of ion transport across biological membranes. Here, we will briefly summarize current knowledge of the molecular mechanisms of how polyP can be involved in membrane ion transport. We discuss three types of mechanisms that might involve polyP: (1) formation of non-protein channel complex that includes calcium, polyP, and polyhydroxybutyrate (PHB); (2) modulation of the channel activity of PHBlated protein channels; and (3) direct effects of polyP on the function of the voltage-gated ion channels in the process that do not involve PHB.

Indexed as

Ion TransportPolyphosphatesAnimalsCalciumCell MembraneHumansHydroxybutyratesIon ChannelsProhibitinsCalciumHydroxybutyratesIon ChannelsPHB protein, humanPolyphosphatesProhibitinscalcium channelsion channelsmitochondriamitochondrial permeability transition porespolyphosphate

Identifiers

PMID38630434
PMCPMC12145141
OpenAlexW4394873250

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.