Trial reportEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2024
A randomized controlled trial demonstrating sustained benefit of autologous matrix-induced chondrogenesis (AMIC
Trial report in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02993510 (Randomised Multi-Center Study), which is not on this map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomised Multi-Center Study: Microfracturing With Chondro-Gide® for the Treatment of Isolated Cartilage Defects in the Knee Project-Nr.: 10830-003
Who cites it
7 citing papers in PubMed, 18 citations in OpenAlex.
- Treatment Options for Focal Cartilage Lesions of the Knee.Deutsches Arzteblatt international · 2026Review
- A Prospective Clinical and Magnetic Resonance Imaging-Based Follow-up Beyond 10 Years After Arthroscopic Matrix-Induced Autologous Chondrocyte Implantation.The American journal of sports medicine · 2026Article
- [Treatment of cartilage defects of the knee].Orthopadie (Heidelberg, Germany) · 2026Article
- Adjuvant injection therapies following knee cartilage repair demonstrate heterogeneous evidence: A systematic review.Journal of experimental orthopaedics · 2025Review
- AMIC achieves sustained clinical improvement in isolated patellar cartilage defects over 5 years, correlating with MRI.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- [Patellar cartilage repair-current concepts and evidence].Orthopadie (Heidelberg, Germany) · 2025Review
- Emerging Strategies in Cartilage Repair and Joint Preservation.Medicina (Kaunas, Lithuania) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAutologous matrix-induced chondrogenesis (AMIC
methodsForty-seven patients were randomized and treated either with MFx (n = 13), sutured AMIC
resultsAll treatment arms improved in the first 2 years, but a progressive and significant deterioration in scores was observed in the MFx group, while both AMIC
conclusionThe AMIC CLINICALTRIALS: gov Identifier: NCT02993510.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.