Evidence map›Paper›PMID 38630278›Full record

ArticleWorld journal of urology2024

Multicenter evaluation of complex urinary diversion for renal transplantation: outcomes of complex surgical solutions.

Luka Flegar, Johannes Huber, Juliane Putz, Christian Thomas, Hendrik Apel, Bernd Wullich, Frank Friedersdorff, Guido Fechner, Manuel Ritter, Karoline Kernig and 5 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

Luka FlegarDepartment of Urology, Philipps-University Marburg, Baldinger Street, 35043, Marburg, Germany. luka.flegar@uk-gm.de.
Johannes HuberDepartment of Urology, Philipps-University Marburg, Baldinger Street, 35043, Marburg, Germany.
Juliane PutzDepartment of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Christian ThomasDepartment of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Hendrik ApelDepartment of Urology and Pediatric Urology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Bernd WullichDepartment of Urology and Pediatric Urology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Frank FriedersdorffDepartment of Urology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Guido FechnerDepartment of Urology, University Medical Center Bonn (UKB), Bonn, Germany.
Manuel RitterDepartment of Urology, University Medical Center Bonn (UKB), Bonn, Germany.
Karoline KernigDepartment of Urology, University Rostock, Rostock, Germany.
Karl WeigandDepartment of Urology, University Hospital Halle (Saale), Halle (Saale), Germany.
Hans HeynemannDepartment of Urology, University Hospital Halle (Saale), Halle (Saale), Germany.
Michael StöckleDepartment of Urology and Pediatric Urology, Saarland University, Homburg/Saar, Germany.
Philip ZeuschnerDepartment of Urology and Pediatric Urology, Saarland University, Homburg/Saar, Germany.
Working Group Kidney Transplantation of the German Association of Urology
Philipps University of Marburg · DESaarland University · DEUniversity Hospital in Halle · DEUniversitätsklinikum Erlangen · DETU Dresden · DEUniversity Hospital Carl Gustav Carus · DEUniversity of Rostock · DECharité - Universitätsmedizin Berlin · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEHumboldt-Universität zu Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAn abnormal lower urinary tract poses significant challenges for transplant surgeons. Besides the ureteral anastomosis to an ileal conduit, there are diverse complex reconstructive solutions. Due to its rarity, standardization and teaching of complex urinary diversion is extremely difficult.

methodsThe indications and outcomes of complex urinary diversions after kidney transplantation (KT) were retrospectively investigated at eight urologic transplant centers including a current follow-up.

resultsOf 37 patients with 21 (56%) males, vesicoureteral reflux (24%), spina bifida (22%), and glomerulonephritis (12%) were the most common causes of terminal renal failure. In 30 (81%) patients, urinary diversion was performed before KT, at a median of 107.5 (range, 10; 545) months before. Transplantations were held at a median patient age of 43 (10; 68) years, including six (16%) living donations. Urinary diversion was modified during 12 (32%) transplantations. After KT, the ileal conduit was the most common incontinent urinary diversion in 25 (67%) patients; a Mainz pouch I and bladder augmentation were the most frequent continent diversions (each n = 3). At a median follow-up of 120 months (range 0; 444), 12 (32%) patients had a graft failure with a 5-year graft survival of 79% (95%CI 61; 90). The median overall survival was 227 months (168; 286) and the 5-year overall survival 89% (69.3; 96.4).

conclusionThe mid-term kidney transplant function with complex urinary diversion appears to be comparable to transplants with regular urinary diversions. Hence, complex urinary diversion should always be considered as a surgical option, even during transplantation, if necessary.

Indexed as

Kidney TransplantationPlastic Surgery ProceduresSurgeonsUrinary DiversionAdultFemaleHumansMaleRetrospective StudiesDialysisIleal conduitKidney transplantationRenal insufficiencyUrinary diversion

Identifiers

PMID38630278
PMCPMC11023965
OpenAlexW4394873614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.