ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2024
Epidemiology and risk factors for fat embolism in isolated lower extremity long bone fractures.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 1 citations in OpenAlex.
- Impact of pediatric obesity on surgical outcomes of lower extremity fractures: a nationwide analysis (2010-2019).BMC musculoskeletal disorders · 2026Article
- Incidence, mortality, and factors associated with fat embolism syndrome in patients with long bone fractures at a trauma referral center in Bogotá, Colombia: 2016-2019 and 2022-2023.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Case Report: Atypical posttraumatic fat embolism syndrome: a case of rapidly progressive respiratory failure precipitated by a finger crush injury.Frontiers in medicine · 2026Article
- Triglyceride-glucose index as a key predictor of ARDS in acute pancreatitis: SHAP analysis reveals its critical role in risk stratification.Frontiers in nutrition · 2025Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
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Abstract
purposeFat embolism syndrome (FES) is a serious complication after orthopedic trauma. The aim of this study was to identify risk factors for FES in isolated lower extremity long bone fractures.
methodsThe National Trauma Data Bank "NTDB" study included patients with isolated femoral and tibial fractures. A total of 344 patients with FES were propensity score matched with 981 patients without FES. Multivariate logistical regression was used to identify independent risk factors for FES.
resultsFES was diagnosed in 344 (0.03%) out of the 1,251,143 patients in the study populations. In the two matched groups, the mortality was 7% in the FES group and 1% in the No FES group (p < 0.001). FES was associated with an increased risk of ARDS, VTE, pneumonia, AKI, and stroke. Younger age, femur fractures, obesity, and diabetes mellitus were independent predictors of FES. Early operative fixation (≤ 48 h) was protective against FES.
conclusionFES increases mortality by seven times. Young age, obesity, and diabetes mellitus are significant independent risk factors for FES. Early fixation is independently associated with a reduced risk of FES. LEVEL OF EVIDENCE: Level III. STUDY TYPE: Prognostic study.
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