Evidence map›Paper›PMID 38629767›Full record

ArticleClinical pediatrics2024

Evaluating the Effect of Maternal Opioid Maintenance Dose on the NOWS-COS Outcome Criteria: A Pilot Study.

Danielle Smith, Rhea Sullivan, Emma C Allen, Sandeep Pradhan, Junjia Zhu, Christiana N Oji-Mmuo

Abstract read
In one paragraph

Article in Clinical pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Danielle SmithDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Penn State College of Medicine, Hershey, PA, USA.ORCID 0000-0002-4302-004X
Rhea SullivanDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Penn State College of Medicine, Hershey, PA, USA.ORCID 0000-0003-0725-6386
Emma C AllenDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Penn State College of Medicine, Hershey, PA, USA.
Sandeep PradhanDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA.
Junjia ZhuDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA.
Christiana N Oji-MmuoDepartment of Pediatrics, Dell Medical School, The University of Texas at Austin, Austin, TX, USA.

Funding

Understanding the miRNA response to opioid withdrawal and their uses as potential biomarkers for neonatal abstinence syndromeF30DA057094 · NIDA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Rhea Elena Sullivan · 2022 to 2026
$213k
NIDA NIH HHS F30 DA057094
6 · The paper itself

Abstract

This retrospective cohort study included 77 mother-infant dyads that delivered term pregnancies at a single tertiary care institution. The primary objective was to investigate whether maternal dose of opioid maintenance therapy during pregnancy affects infant outcomes. All infants had prenatal exposure to opioid maintenance therapies. Maternal dose was converted into morphine milligram equivalents (MMEs) and stratified into high- (MME >1000 mg) and low-dose groups (MME ≤1000 mg). Associations between infant outcomes and MME dosage were examined using Wilcoxon rank-sum and Fisher's Exact tests. Days to symptom control were significantly higher in the high MME group (5 days vs 2.8 days,

Indexed as

Analgesics, OpioidAdultCohort StudiesDevelopmental DisabilitiesDose-Response Relationship, DrugFemaleHumansInfantInfant, NewbornMaleMethadoneNeonatal Abstinence SyndromeOpiate Substitution TreatmentOpioid-Related DisordersPilot ProjectsPregnancyAnalgesics, OpioidMethadonebuprenorphinedelaydevelopmentalMMENOWSopioid

Identifiers

PMID38629767
PMCPMC11539537

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.