Evidence map›Paper›PMID 38629685›Full record

SynthesisJournal of adolescent and young adult oncology2024

A Systematic Review of the Gonadotoxicity of Osteosarcoma and Ewing's Sarcoma Chemotherapies in Postpubertal Females and Males.

Susanna Weidlinger, Satu Graber, Irina Bratschi, Janna Pape, Attila Kollár, Tanya Karrer, Michael von Wolff

Registry-linked trialOpen access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Journal of adolescent and young adult oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05885048 (FertiTOX - Platform for Fertility Related Gonadotoxicity of Cancer Therapies), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05885048 recruitingnot on this map

FertiTOX - Platform for Fertility Related Gonadotoxicity of Cancer Therapies

Typeobservational_patient_registrySponsorMichael von WolffRan2023 to 2038Enrolled7,000ConditionsCancer, Fertility Issues, Fertility Preservation, Toxicity Due to ChemotherapyArmsBlood samples for analysis, Sperm samples for analysis, Satisfaction evaluation, Quality of Life questionnaire
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Susanna WeidlingerDivision of Gynecological Endocrinology and Reproductive Medicine, University Women's Hospital, Inselspital Bern, University of Bern, Bern, Switzerland.
Satu GraberDivision of Gynecological Endocrinology and Reproductive Medicine, University Women's Hospital, Inselspital Bern, University of Bern, Bern, Switzerland.
Irina BratschiDivision of Gynecological Endocrinology and Reproductive Medicine, University Women's Hospital, Inselspital Bern, University of Bern, Bern, Switzerland.
Janna PapeDivision of Gynecological Endocrinology and Reproductive Medicine, University Women's Hospital, Inselspital Bern, University of Bern, Bern, Switzerland.
Attila KollárDepartment of Medical Oncology, Inselspital Bern, University of Bern, Bern, Switzerland.
Tanya KarrerMedical Library, University Library Bern, University of Bern, Bern, Switzerland.
Michael von WolffDivision of Gynecological Endocrinology and Reproductive Medicine, University Women's Hospital, Inselspital Bern, University of Bern, Bern, Switzerland.ORCID 0000-0003-4303-2734
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data on gonadotoxicity of chemotherapies are essential to better counsel young females and males about the risk of infertility and to better indicate fertility preservation measures before cancer therapies. However, such data have not recently been reviewed for bone cancer. Therefore, a systematic literature search was conducted considering papers published since 2000. This study is part of the FertiTOX

Indexed as

Antineoplastic AgentsBone NeoplasmsOsteosarcomaSarcoma, EwingFemaleFertility PreservationHumansMaleAntineoplastic Agentsamenorrheaanti-mullerian hormonechemotherapyEwing’s sarcomafertilityFertiPROTEKTFertiTOXgonadotoxicityosteosarcomaradiotherapysperm count

Identifiers

PMID38629685
PMCPMC11322626
OpenAlexW4394874310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.