ArticleArquivos brasileiros de cardiologia2024
The Systemic Immune-Inflammation Index Predicts In-Hospital Mortality in Patients Who Underwent On-Pump Cardiac Surgery.
Article in Arquivos brasileiros de cardiologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.
- Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis.Journal of cardiothoracic surgery · 2025Pooled it
- Dynamic Perioperative Risk Stratification of In-Hospital Mortality After Elective Isolated On-Pump CABG: A Single-Center Firth Penalized Logistic Regression Analysis.Journal of clinical medicine · 2026Article
- Elevated Preoperative Systemic Immune-Inflammation Index Independently Predicts 30-Day Mortality After Living Donor Liver Transplantation.Life (Basel, Switzerland) · 2026Article
- Does Inflammatory Prognostic Index Predict Postoperative Outcomes in Coronary Artery Bypass Grafting?Journal of clinical medicine · 2026Article
- A Composite Indicator of Inflammation and Nutritional Status for Predicting Mortality After CABG: The CRP-to-Albumin Ratio.Nutrients · 2026Article
- Risk Stratification for Postoperative Mortality in Cardiac Surgery: "Quo Vadis"?Medicina (Kaunas, Lithuania) · 2026Review
- Inflammation-Based Hematologic Indices as Prognostic Markers in Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension: A Hypothesis-Generating Registry Study.International journal of molecular sciences · 2025Article
- SII and lung cancer in middle-aged and elderly population: the nonlinear connection and the mediating role of ABSI.World journal of surgical oncology · 2025Article
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6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundSystemic immune-inflammation index (SII), a new inflammatory index calculated using platelet, neutrophil, and lymphocyte counts, has been demonstrated to be an independent risk factor for the identification of high-risk coronary artery disease in patients undergoing percutaneous coronary intervention and cardiovascular surgery with cardiopulmonary bypass (CPB). The relationship between SII and CPB-related mortality rates remains unclear.
objectiveThis research was designed to investigate the use of SII to predict in-hospital mortality in patients undergoing cardiac surgery with CPB.
methodsFour hundred eighty patients who underwent a cardiac procedure involving CPB over 3 years, were obtained from the hospital's database. The demographic data, comorbidities, hematological and biochemical profiles, and operative data of the groups were compared. Multiple logistic regression analyses were done to determine independent predictors of mortality. Prognostic factors were assessed by multivariate analysis, and the predictive values of SII, neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) for mortality were compared. A p-value <0.05 was considered significant.
resultsOf 480 patients, 78 developed in-hospital mortality after cardiac surgery. SII was an independent predictor of in-hospital mortality (Odds ratio: 1.003, 95% confidence interval: 1.001-1.005, p<0.001). The cut-off value of the SII was >811.93 with 65% sensitivity and 65% specificity (area under the curve: 0.690). The predictive values of SII, PLR, and NLR were close to each other.
conclusionHigh preoperative SII scores can be used for early determination of appropriate treatments, which may improve surgical outcomes of cardiac surgery in the future.
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