Evidence map›Paper›PMID 38628606›Full record

ArticleJournal of clinical imaging science2024

Iodine quantification of renal lesions: Preliminary results using spectral-based material extraction on photon-counting CT.

Adrienn Tóth, Jordan H Chamberlin, Salvador Mendez, Akos Varga-Szemes, Andrew D Hardie

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Article in Journal of clinical imaging science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Adrienn TóthDepartment of Radiology and Radiological Science, Medical University of South Carolina, Charleston, South Carolina, United States.
Jordan H ChamberlinDepartment of Radiology and Radiological Science, Medical University of South Carolina, Charleston, South Carolina, United States.
Salvador MendezDepartment of Radiology and Radiological Science, Medical University of South Carolina, Charleston, South Carolina, United States.
Akos Varga-SzemesDepartment of Radiology and Radiological Science, Medical University of South Carolina, Charleston, South Carolina, United States.
Andrew D HardieDepartment of Radiology and Radiological Science, Medical University of South Carolina, Charleston, South Carolina, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To assess the range of quantitative iodine values in renal cysts (RC) (with a few renal neoplasms [RNs] as a comparison) to develop an expected range of values for RC that can be used in future studies for their differentiation. Material and Methods: Consecutive patients ( Results: A total of 259 renal lesions (243 RC and 16 RN) were analyzed. There were significant differences between RC and RN for all IC measures with the best-performing metrics being mean and maximum IC of the entire lesion ROI (AUC 0.912 and 0.917, respectively) but also mean and minimum IC of the most suspicious area in heterogeneous lesions (AUC 0.983 and 0.992, respectively). Most RC fell within a range of low measured iodine values although a few had higher values. Conclusion: Automated iodine quantification maps reconstructed from clinical PCCT have a high diagnostic ability to differentiate RCs and neoplasms. The data from this pilot study can be used to help establish quantitative values for clinical differentiation of renal lesions.

Indexed as

Iodine quantificationPhoton-counting computed tomographyRenal lesion

Identifiers

PMID38628606
PMCPMC11021115

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.