Evidence map›Paper›PMID 38628556›Full record

ArticleBiology methods & protocols2024

Intra-arterial delivery of neurospheres into isolated perfused porcine colons: a proof of concept.

Richard D Martel, Nicolas A Hoyos, María Ángeles Tapia-Laliena, Irmgard Herrmann, Martin Herrmann, Rasul Khasanov, Karl-Herbert Schäfer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology methods & protocols, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Richard D MartelDepartment of Pediatric Surgery, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Heidelberg, Germany.ORCID https://orcid.org/0000-0003-4850-5246
Nicolas A HoyosDepartment of Pediatric Surgery, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Heidelberg, Germany.
María Ángeles Tapia-LalienaDepartment of Pediatric Surgery, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Heidelberg, Germany.
Irmgard HerrmannDepartment of Medicine 3, Universitäts-Klinikum Erlangen, Erlangen, Germany.
Martin HerrmannDepartment of Pediatric Surgery, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Heidelberg, Germany.
Rasul KhasanovDepartment of Pediatric Surgery, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Heidelberg, Germany.
Karl-Herbert SchäferEnteric Nervous System Group, University of Applied Sciences Kaiserslautern, Zweibrücken, Germany.
Heidelberg University · DEUniversitätsklinikum Erlangen · DEUniversity of Applied Sciences Kaiserslautern · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell replacement in aganglionic intestines is a promising, yet merely experimental tool for the therapy of congenital dysganglionosis of the enteric nervous system like Hirschsprung disease. While the injection of single cells or neurospheres to a defined and very restricted location is trivial, the translation to the clinical application, where large aganglionic or hypoganglionic areas need to be colonized (hundreds of square centimetres), afford a homogeneous distribution of multiple neurospheres all over the affected tissue areas. Reaching the entire aganglionic area

Indexed as

cell therapyenteric nervous systemHirschsprung diseaseintra-arterialneurosphere

Identifiers

PMID38628556
PMCPMC11018533
OpenAlexW4393407386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.