Evidence map›Paper›PMID 38628497›Full record

ArticleAustin journal of medical oncology2020

Functional Significance of Mirna-149 in Lung Cancer: Can it be Utilized as a Potential Biomarker or a Therapeutic Target?

S J Chauhan, A Thyagarajan, R P Sahu

Open access · bronzeAbstract read
In one paragraph

Article in Austin journal of medical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S J ChauhanDepartment of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, USA.
A ThyagarajanDepartment of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, USA.
R P SahuDepartment of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, USA.
Wright State University · US

Funding

Environmental pro-oxidative stressors and immunosuppressionK22ES023850 · NIEHS · WRIGHT STATE UNIVERSITY · PI SAHU, RAVI PRAKASH · 2014 to 2016
$488k
NIEHS NIH HHS K22 ES023850
6 · The paper itself

Abstract

Accumulating evidence has documented the significance of miR-149 as a promising tumor-suppressive non-coding RNA that play critical roles in regulating genes involved in cancer growth and metastasis. Notably, the ability of miR-149 to be utilized as a potential biomarker in the diagnosis/prognosis or a therapeutic target has also been explored using various cellular and preclinical models, as well as in clinical settings of lung cancer. While the applicability of miR-149 in assessing tumor progression has been suggested, its potential in predicting treatment outcomes is needed to be verified in diverse settings of lung cancer patients. The current review presents an overview of the functional significance of miR-149 with ongoing challenges in non-small cell lung cancer.

Indexed as

Cancer therapyLung cancermiR-149

Identifiers

PMID38628497
PMCPMC11019914
OpenAlexW3138066054

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.