Evidence map›Paper›PMID 38628198›Full record

ArticleFood science & nutrition2024

Sinapic acid modulates oxidative stress and metabolic disturbances to attenuate ovarian fibrosis in letrozole-induced polycystic ovary syndrome SD rats.

Huan Lan, Zhe-Wen Dong, Ming-Yu Zhang, Wan-Ying Li, Chao-Jie Chong, Ya-Qi Wu, Zi-Xian Wang, Jun-Yang Liu, Zhi-Qiang Liu, Xiao-Hui Qin and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Reproductive and Cardiometabolic Characterization of a Letrozole- and High-Fat Diet-Induced PMOS-like Rat Model: An Experimental Study.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
  2. Article
  3. Article
  4. Molecular mechanisms of ovarian fibrosis.Molecular human reproduction · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Food science & nutrition · 2024
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Huan LanGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.
Zhe-Wen DongGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.
Ming-Yu ZhangGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.
Wan-Ying LiGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.
Chao-Jie ChongGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.
Ya-Qi WuGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.
Zi-Xian WangGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.
Jun-Yang LiuGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.
Zhi-Qiang LiuGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.
Xiao-Hui QinGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.
Tie-Min JiangSouth Asia Branch of National Engineering Center of Dairy for Maternal and Child Health Guilin University of Technology Guilin Guangxi China.
Jia-Le SongGuangxi Key Laboratory of Environmental Exposureomics and Entire Lifecycle Health Guilin Medical University Guilin Guangxi China.ORCID https://orcid.org/0000-0001-6269-5846
Guilin Medical University · CNGuangzhou University of Chinese Medicine · CNGuilin University of Technology · CNShenyang Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sinapic acid (SA) is renowned for its many pharmacological activities as a polyphenolic compound. The cause of polycystic ovary syndrome (PCOS), a commonly encountered array of metabolic and hormonal abnormalities in females, has yet to be determined. The present experiment was performed to evaluate the antifibrotic properties of SA in rats with letrozole-induced PCOS-related ovarian fibrosis. SA treatment successfully mitigated the changes induced by letrozole in body weight (BW) (

Indexed as

fibrosismetabolic disturbancesoxidative stresspolycystic ovary syndromesinapic acidTGF‐β1/Smads

Identifiers

PMID38628198
PMCPMC11016395
OpenAlexW4391228709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.